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Efonidipine hydrochloride monoethanolate

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Formula: C36H45ClN3O8P
CAS: 111011-76-8

Identification

Structural Formula
Efonidipine hydrochloride monoethanolate
CAS:
111011-76-8
EINECS:
Molecular Formula:
C36H45ClN3O8P
MDL:
SMILES:
CCO.CC1=C(C(C(=C(N1)C)P2(=O)OCC(CO2)(C)C)C3=CC(=CC=C3)[N+](=O)[O-])C(=O) OCCN(CC4=CC=CC=C4)C5=CC=CC=C5.Cl
Synonym:
ethanol ; r,p-oxide,monohydrochloride ; efonidipine hydrochloride ethanolate ; efonidipine hydrochloride (jan) ; efonidipinehydrochlorideethanolate ; efonidipine hydrochloride ethanol ; landel (tn) ; 3-pyridinecarboxylicacid,1,4-dihydro-2,6-dimethyl-5-(5,5-dimethyl-1,3,2-dioxa ; 1) ; nz105ethanolate ; ethanol, compd. with 2-(phenyl(phenylmethyl)amino)ethyl 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylate monohydrochloride ; nz-105 ; efonidipine hydrochloride monoethanolate ; nz 105 ethanolate ; 2-(phenyl(phenylmethyl)amino)ethyleste ; 3-pyridinecarboxylic acid, 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-(phenyl(phenylmethyl)amino)ethyl ester, monohydrochloride, compd. with ethanol (1 ; 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylicacid2-[phenyl(phenylmethyl)amino]ethylesterhydrochloridemonoethanolate ; 2-(benzyl-phenyl-amino)ethyl 5-(5,5-dimethyl-2-oxo-1,3-dioxa-2$l^c36h45cln3o8p-phosphacyclohex-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate ; efonidipine hydrochloride ; hydrochloride ; efonidipine.hcl ethanolate ; 3-pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yl)-4-(3-nitrophenyl)-, 2-(phenyl(phenylmethyl)amino)ethyl ester, p-oxide, monohydrochloride ; landel


Description

Racemic efonidipine has both L-type and T-type calcium channel protein inhibitor activity. The R(−)-isomer appears to be very selective for T-type calcium channel. The S(+)-isomer inhibits the expressed Ca(V)1.2, Ca(V)1.3 and Ca(V)3.1 channel currents almost equally.


Suppliers

CSNpharm, Inc.
CSN10893
Santa Cruz Biotechnology, Inc.
364486
Dayang Chem (Hangzhou) Co.,Ltd.
DC372014880
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Prices & Availability




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Properties for Efonidipine hydrochloride monoethanolate

Molecular Weight:
714.1846 g·mol−1
Density:
1.3 g/cm3
Boiling point:
746.9 °C at 760 mmHg
Flash point:
405.5 °C
Solubility:
>5 mg/mL in DMSO
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Safety & Transport Information

Storage temperature :
Desiccate at +4 °C
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Alternative Distributors of [Efonidipine hydrochloride monoethanolate]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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MSDS:
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