Fluocinolone Acetonide | CAS 67-73-2

Element: fluocinolone acetonide

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C-S » Chemicals » fluocinolone-acetonide-PX63452

Identification

Fluocinolone Acetonide

CAS:

67-73-2

EINECS:

200-668-5

Molecular Formula:

C₂₄H₃₀F₂O₆

MDL:

MFCD00010525

SMILES:

CC1(OC2CC3C4CC(C5=CC(=O)C=CC5(C4(C(CC3(C2(O1)C(=O)CO)C)O)F)C)F)C

Synonym:

fluonid ; localyn ; fluzon ; synamol ; sinalar ; radiocin ; synalar ; jellin ; synsac ; dermalar

Description

Fluocinolone Acetonide is a synthetic glucocorticoid which acts as an inhibitor of tumor cells. Studies indicate that Fluocinolone Acetonide can inhibit promotion of tumor cells at an early stage of promotion if combined with a promoting agent. In addition, studies suggest that Fluocinolone Acetonide can regulate lipid metabolism by modulating gene expression. Alternate studies show that Fluocinolone Acetonide can inhibit the expression of VEGF (vascular endothelial growth factor) in the retinal pigment epithelial cell line due to its high glucocorticoid receptor affinity. Furthermore, Fluocinolone Acetonide can inhibit TNF-α angiogenesis.

Suppliers

H&Z Industry Co.,Ltd

HIC8803520

Coral Drugs Pvt. Ltd.

CDP9243696

Guangzhou Topwork Chemical Co., Ltd.

GTC15846336

Austin Chemical Company, Inc.

ACC12765104

Alfa (A Johnson Matthey Company)

A14084224

X´ian Taicheng Chem Co., Ltd

XTC12765104

BoomKing Industrial Co.,Limited

BIC13645456

Caesar & Loretz GmbH

CL8802640

Sancai Industry Co.,Ltd.

SIC10564224

Aecochem Corp.

AC6161848

CSNpharm, Inc.

CSN11031

Hangzhou Lingrui Chemical Co., Ltd.

HLC15406160

Sigma-Aldrich International GmbH

SI14084224

Hefei Hirisun Pharmatech Co., Ltd

HS010002

AK Scientific, Inc.

AS8362508

Santa Cruz Biotechnology, Inc.

204756

Dayang Chem (Hangzhou) Co.,Ltd.

DC13645456

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Prices & Availability

Data is processed

Properties for Fluocinolone Acetonide

Molecular Weight:

452.49 g·mol−1

Density:

~1.4 g/cm³ (Predicted)

Melting point:

267-269 °C(lit.)

Boiling point:

~578.5° C at 760 mmHg (Predicted)

Solubility:

Soluble in water (partly), DMSO, alcohol ( ), chloroform, and methanol.

Safety & Transport Information

Risk Codes:

R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R40 - Limited evidence of a carcinogenic effect

Safety Codes:

S22 - Do not breathe dust
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Symbols:

Xi, Xn

Storage temperature :

Refrigerator

Alternative Distributors of [Fluocinolone Acetonide]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified