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(R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3,3-dimethylpentanoic acid

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CAS: 1310680-40-0

Identification

Structural Formula
(R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3,3-dimethylpentanoic acid
CAS:
1310680-40-0
EINECS:
Molecular Formula:
MDL:
Synonym:


Description

beta,beta-Dimethylation of amino acids stabilizes appropriate peptides towards digestion by proteases. Reference: Total synthesis of the large non-ribosomal peptide polytheonamide B; Masayuki Inoue, Naoki Shinohara, Shintaro Tanabe, Tomoaki Takahashi, Ken Okura, Hiroaki Itoh, Yuki Mizoguchi, Maiko Iida, Nayoung Lee and Shigeru Matsuoka; Nature Chem. 2010; 2: 281-285. DOI: 10.1038/nchem.554.


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