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9-Fluorenylmethyloxycarbonyl-valyl-alanyl-4-aminobenzylalcohol

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CAS: 1394238-91-5

Identification

Structural Formula
9-Fluorenylmethyloxycarbonyl-valyl-alanyl-4-aminobenzylalcohol
CAS:
1394238-91-5
EINECS:
Molecular Formula:
MDL:
Synonym:


Description

Linker for Antibody-Drug-Conjugation (ADC). The Val-Cit will specifically be cleaved by catepsin B. As this enzyme is only present in the lysosome the ACD payload will be release only in the cell. Reference: Laurent Ducry (ed.), Antibody-Drug Conjugates, Methods in Molecular Biology, vol. 1045, DOI 10.1007/978-1-62703-541-5_5, # Springer Science+Business Media, LLC 2013.


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Iris Biotech GmbH
ADC1060
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