Identification
9-Fluorenylmethyloxycarbonyl-valyl-citrullyl-(4-aminobenzyl)-(4-nitrophenyl)carbonate
Molecular Formula:
C3 3 H3 9 N5 O6
Description
Linker for Antibody-Drug-Conjugation (ADC). The Val-Cit will specifically be cleaved by catepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. Reference: Laurent Ducry (ed.), Antibody-Drug Conjugates, Methods in Molecular Biology, vol. 1045, DOI 10.1007/978-1-62703-541-5_5, # Springer Science+Business Media, LLC 2013.
Suppliers
Iris Biotech GmbH
ADC1030
CAS equal suppliers
Fmoc-Val-Cit-PAB
Iris Biotech GmbH
ADC1030.0250
Fmoc-Val-Cit-PAB
ShangHai Biochempartner Co., Ltd.
BCP13071
Fmoc-Val-Cit-PAB
Excenen Pharmatech Co., Ltd.
EN-3276
Fmoc-Val-Cit-PAB
Gihi Chemicals Co., Limited
GCL4321728
Fmoc-Val-Cit-PAB
Shanghai Haoyuan Chemexpress Co., Ltd.
SHC6082432
Fmoc-Val-Cit-PAB
Amadis Chemical Company Limited
ACCL4962480
Fmoc-Val-Cit-PAB
BOC Sciences
BS192576
Fmoc-Val-Cit-PAB
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI11044416
Fmoc-Val-Cit-PAB
BLD Pharmatech Ltd
BP288864
Fmoc-Val-Cit-PAB-OH
Ambeed, Inc.
A192152
Fmoc-Val-Cit-PAB-OH
CSNpharm, Inc.
CSN13652
9H-Fluoren-9-ylmethyl N-[(2S)-1-[[(2S)-5-(carbamoylamino)-1-[4-(hydroxymethyl)anilino]-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate
Finetech Industry Limited
FIL87000348000
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