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Furosemide

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Formula: C12H11ClN2O5S
CAS: 54-31-9
search Element: furosemide

Identification

Structural Formula
Furosemide
CAS:
54-31-9
EINECS:
200-203-6
Molecular Formula:
C12H11ClN2O5S
MDL:
MFCD00010549
SMILES:
NS(=O)(=O)C1=C(Cl)C=C(NCC2=CC=CO2)C(=C1)C(O)=O
Synonym:
laxur ; mirfat ; "mita" ; frumide ; 5-(aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)amino]benzoic acid ; frusedan ; urex-m ; rusyde ; uritol ; eris ; urian ; furex ; furosan ; diurin ; lasex ; depix ; 4-chloro-2-(2-furylmethylamino)-5-sulfamoyl-benzoic acid ; fusid ; furix ; lasix ; furosifar ; puresis ; furanthril ; aquarid ; franyl ; jenafusid ; salix ; aldic ; lazax ; furosix ; prefemin ; neo-renal ; chlor-n- (2-furylmethyl)-5-sulfamylanthranilsaeure ; bioretic


Description

Furosemide is a loop diuretic inhibitor of NKCC (Na+/2Cl-/K+) cotransporter. Furosemide acts as a non-competitive antagonist at GABAA receptors with ~ 100-fold greater selectivity for α6-containing receptors than α1-containing receptors.


Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI6902760
H&Z Industry Co.,Ltd
HIC200800
Shandong SanYoung Industry Co., Ltd
SSI3501400
XD BIOCHEMS Ltd
XB150450
WG Critical Care, LLC
WCCL2101050
Pharma Greven GmbH
PG180540
B.M.P. Bulk Medicines & Pharmaceuticals GmbH
BBMP4402200
CellMark AB
CA110330
AXO Industry SA
AIS150600
Hangzhou Verychem Science & Technology Co., Ltd.
HVST4802400
Xiamen Equation Chemical Co.,Ltd
XECC3201600
Aecochem Corp.
AC140420
Hangzhou Keying Chem Co., Ltd.
HKC3001200
Sigma-Aldrich International GmbH
SI320960
scienTEST - bioKEMIX GmbH
S-B2501000
Carbone Scientific Co., Ltd.
CS280840
AK Scientific, Inc.
AS190570
Capot Chemical Co., Ltd.
7165
Leap Chem Co., Ltd
LC180540
Santa Cruz Biotechnology, Inc.
203961
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CAS equal suppliers

Frusemide
Gihi Chemicals Co., Limited
GCL243972
Frusemide
LGM Pharma
LP90270
Frusemide
Exim Corporation
EC144432
Furosemide, 97+%
Alfa (A Johnson Matthey Company)
A5121536
Furosemide (Frusemide)
Molekula
29949072
Benzoic acid, 5-(aminosulfonyl)-4-chloro-2-[(2-furanylmethyl)amino]-
Angene International Limited
AGN-PC-00PO4Z

Prices & Availability




Data is processed


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Properties for Furosemide

Molecular Weight:
330.76 g·mol−1
Density:
1.606 g/cm3
Melting point:
220 °C (dec.)(lit.)
Boiling point:
582.1 °C at 760 mmHg
Flash point:
305.9 °C
Solubility:
Soluble in DMSO (66 mg/ml at 25° C), ethanol (<1 mg/ml at 25° C), water (<1 mg/ml at 25° C), methanol (50 mg/ml), and DMF.
Physical Description:
white to light yellow crystal powder
Transport Information:
UN 1230 3/PG 2
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Hazard Statements

GHS08

GHS08
Health hazard
  • Respiratory sensitization, category 1
  • Germ cell mutagenicity, categories 1A, 1B, 2
  • Carcinogenicity, categories 1A, 1B, 2
  • Reproductive toxicity, categories 1A, 1B, 2
  • Specific target organ toxicity following single exposure, categories 1, 2
  • Specific target organ toxicity following repeated exposure, categories 1, 2
  • Aspiration hazard, categories 1, 2

Safety & Transport Information

Risk Codes:
R11 - Highly flammable
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed
R61 - May cause harm to the unborn child
Safety Codes:
S16 - Keep away from sources of ignition - No smoking
S22 - Do not breathe dust
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S36/37 - Wear suitable protective clothing and gloves
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use
S7 - Keep container tightly closed
Hazard Symbols:
T, F, Xi
Hazard symbol T Hazard symbol F Hazard symbol Xi
Storage temperature :
2-8°C
RID/ADR certification :
UN 1230 3 / PG 2
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Alternative Distributors of [Furosemide]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | Xinchem Corporation | Watson International Ltd | 3B Scientific Corporation | Shanghai Eagle Chemical Co., Ltd. | Jiangsu Guotai International Group Co., Ltd. | Unispec Chemicals Co. | Molekula GmbH | Nantong Chem-Tech. (Group) Co., Ltd. | Ningbo Pangs Chem Int'l Co., Ltd. | TCI Europe NV | China Yangzhou Wandong Medical Co., Ltd. | New Dragon Industrial Co., Ltd | Chengdu Qiaofeng Technological Development Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Shanghai Boyle Chemical Co., Ltd. | Jinan Great Chemical Co., Ltd. | Ningbo Hi-Tech Biochemicals Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Discovery Fine Chemicals Limited | Pharmfar Co., Ltd. | BOC Sciences | C-LAB Chemievermittlung GmbH | Jinan Haohua Industry Co., Ltd. | Trademax Phamaceuticals & Chemicals Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Haihang Industry Co., Ltd. | scienTEST | Clearsynth Canada INC.

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