N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala | CAS 78832-65-2

Element: acryloyl furyl

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C-S » Chemicals » furyl-acryloyl-leu-gly-pro-ala-PX50943

Identification

N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala

CAS:

78832-65-2

EINECS:

Molecular Formula:

C₂₃H₃₂ N₄ O₇

MDL:

MFCD00133552

SMILES:

CC(C)CC(C(=O)NCC(=O)N1CCCC1C(=O)NC(C)C(=O)O)NC(=O)/C=C/C2=CC=CO2

Synonym:

collagenase substrate ii ; fa-leu-gly-pro-ala-oh ; collagenaseâ…£ ; l-alanine,n-[1-[n-[n-[3-(2-furanyl)-1-oxo-2-propenyl]-l-leucyl]glycyl]-l-prolyl]- ; falgpa ; collagenaseâ…¡ ; collagenase grade i ; l-alanine,n-[3-(2-furanyl)-1-oxo-2-propenyl]-l-leucylglycyl-l-prolyl- (9ci) ; clostridiopeptidase ; l-alanine,n-[3-(2-furanyl)-1-oxo-2-propen-1-yl]-l-leucylglycyl-l-prolyl- ; collagenase grade ii ; collagenaseâ…¤ ; collagenaseâ…

Description

N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala (FALGPA) is a substrate for the spectrophotometric assay of MMP (collagenase). The isoforms I and II of purified collagenase differ in their specificities and relative activities on native collagen and synthetic substrates. Collagenase II activity is measured by the enzyme's ability to cut a short synthetic peptide, N-[3-(2-Furyl)acryloyl)]-Leu-Gly- Pro-Ala (FALGPA).