GBR 12935 dihydrochloride
Formula: C28H34 N2 O . 2 Cl H
CAS: 67469-81-2
Identification
GBR 12935 dihydrochloride
Molecular Formula:
C2 8 H3 4 N2 O . 2 Cl H
SMILES:
C1CN(CCN1CCCC2=CC=CC=C2)CCOC(C3=CC=CC=C3)C4=CC=CC=C4.Cl.Cl
Synonym:
piperazine,1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)-, hydrochloride (1:2) ; gbr 12935 dihydrochloride ; gbr 12935 dihydrochloride, >=98% ; piperazine,1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)-, dihydrochloride (9ci) ; gbr-12935 2hcl ; gbr 12935 (hydrochloride) ; gbr-2935(dihydrochloride) ; 1-(2-diphenylmethoxyethyl)-4-(3-phenylpropyl)piperazine dihydrochloride ; gbr 12935 hcl
Description
GBR 12935 dihydrochloride inhibits DAT (dopamine transporter) (Ki = 21.5 nM) and SLC6A2 (norepinephrine transporter) (Ki = 225 nM). GBR 12935 does not inhibit the serotonin transporter (Ki = 6.5 μM). GBR 12935 binds to a nondopaminergic piperazine site in blood platelets and brain that has been identified as cytochrome P450.
Suppliers
Alfa (A Johnson Matthey Company)
A16004800
Hangzhou Lingrui Chemical Co., Ltd.
HLC17507000
Santa Cruz Biotechnology, Inc.
203965
CAS equal suppliers
GBR 12935 HCl
ShangHai Biochempartner Co., Ltd.
BCP09762
GBR 12935 2HCl
CSNpharm, Inc.
CSN17054
GBR 12935 (dihydrochloride)
Excenen Pharmatech Co., Ltd.
EX-A451
1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride
Leap Chem Co., Ltd
LC1182635478
1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride
Finipharma Ltd
F919818396
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Properties
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Properties for GBR 12935 dihydrochloride
Molecular Weight:
487.5 g·mol−1
Melting point:
223-225° C
Boiling point:
540.6° C at 760 mmHg (Predicted)
Solubility:
H2 O: 20 mg/mL with warming
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Alternative Distributors of [GBR 12935 dihydrochloride]
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