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Glyburide (Glibenclamide)

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Formula: C23H28ClN3O5S
CAS: 10238-21-8
search Element: glibenclamide glyburide
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Identification

Structural Formula
Glyburide (Glibenclamide)
CAS:
10238-21-8
EINECS:
233-570-6
Molecular Formula:
C23H28ClN3O5S
MDL:
MFCD00056625
SMILES:
COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
Synonym:
daonil ; adiab ; ur606 ; hb 419 ; ur 606 ; hd419 ; u26452 ; hb419 ; malix ; hd 419


Description

Glyburide (Glibenclamide) is a sulfonylurea compound that modulates insulin production. Sulfonylureas bind to ATP-dependent K+ channels in beta cells of the pancreas, depolarizing them and stimulating the release of Ca2+, which in turn stimulates insulin production. Glyburide (Glibenclamide) is an ATP-dependent K+ channel (KIR6, KATP) and CFTR Cl- channel blocker. This compound inhibits recombinant CFTR Cl- channels (IC50 = 20 μM).


Suppliers

Santa Cruz Biotechnology, Inc.
200982
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Prices & Availability




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Properties for Glyburide (Glibenclamide)

Molecular Weight:
494 g·mol−1
Density:
1.4 g/cm3 (Predicted)
Melting point:
173-175 °C
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Safety & Transport Information

Risk Codes:
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
Safety Codes:
S22 - Do not breathe dust
S36 - Wear suitable protective clothing
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Hazard Symbols:
Xn
Hazard symbol Xn
Storage temperature :
2-8°C
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Alternative Distributors of [Glyburide (Glibenclamide)]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences | ABCR GmbH & Co. KG | Molekula GmbH | scienTEST | China Yangzhou Wandong Medical Co., Ltd. | Discovery Fine Chemicals Limited | Haihang Industry Co., Ltd.

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