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15(S)-HETE

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Formula: C20H32O3
CAS: 54845-95-3
search Element: hete

Identification

Structural Formula
15(S)-HETE
CAS:
54845-95-3
EINECS:
Molecular Formula:
C20H32O3
MDL:
MFCD00063590
SMILES:
CCCCC[C@@H](/C=C/C=CC/C=CC/C=CCCCC(=O)O)O
Synonym:
(15s)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate ; 15(s)-hydroxyeicosa-5z,8z,11z,13e-tetraenoic acid ; c04742 ; (15s,5z,8z,11z,13e)-15-hydroxyeicosatetraenoic acid ; icomucret ; 15(s)-hete lipid maps ms standard ; 15(s)-hete ; (s)-15-hete ; (15s)-15-hydroxy-5,8,11-cis-13-trans-eicosatetraenoate ; 15(s)-hydroxy-(5z,8z,11z,13e)-eicosatetraenoic acid


Description

15(S)-HETE (HETE) is a metabolite of arachidonic acid via the 15-lipoxygenase pathway. In mammals HETE is biosynthesised in neutrophils, reticulocytes, eosinophils and respiratory epithelium. It has shown to induce immunosuppression, regulate T lymphocytes and stimulate neovascularization and migration of endothelial cells. It has been observed to inhibit prostaglandin E2 in tumor cells and inhibit cell proliferation in colon cancer cells.


Suppliers

Santa Cruz Biotechnology, Inc.
200944
Santa Cruz Biotechnology, Inc.
sc-200944
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CAS equal suppliers

15(s)-hydroxy-5(z),8(z),11(z),13(e)-eicosatetraenoic acid
Indofine Chemical Co, Inc.
14-2040

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Properties for 15(S)-HETE

Molecular Weight:
320.47 g·mol−1
Density:
0.80 g/cm3
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Safety & Transport Information

Risk Codes:
R11 - Highly flammable
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S16 - Keep away from sources of ignition - No smoking
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S7 - Keep container tightly closed
Hazard Symbols:
F, Xi
Hazard symbol F Hazard symbol Xi
Storage temperature :
-20°C
RID/ADR certification :
UN 1170 3 / PG 2
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Alternative Distributors of [15(S)-HETE]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences

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Downloads

Mol File:
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MSDS:
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