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12(S)-HHT

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Formula: C17H28O3
CAS: 54397-84-1
search Element:

Identification

Structural Formula
12(S)-HHT
CAS:
54397-84-1
EINECS:
Molecular Formula:
C17H28O3
MDL:
MFCD00057833
SMILES:
CCCCC[C@@H](/C=C/C=C/C/C=CCCCC(=O)O)O
Synonym:
12(s)-hht ; 12-hhtre ; 12(s)-hydroxy-5(z),8(e),10(e)-*heptadeca trienoic ac ; 12(s)-hydroxyheptadeca-5z,8e,10e-trienoic acid ; 12(s)-hhtre ; 12(s)-hhtre lipid maps ms standard ; 12(s)-hydroxy-5(z),8(e),10(e)-*heptadecatrienoic ; 12-hydroxy-hepta- decatrienoic acid ; 12-hht ; 12(s)-hydroxy-(5z,8e,10e)-heptadecatrienoic acid


Description

12(S)-HHT is known to inhibit human platelet aggregation. It has been shown to stimulate the production of prostacyclin, an eicosanoid that exerts control over inflammation, immunity, and acts as a central nervous system messenger. 12(S)-HHT is metabolized by 15-hydroxyprostaglandin dehydrogenase to 12-KHT in human erythrocytes. It is also useful as a UV chromophore, and can be used in this manner to measure the metabolism of arachidonic acid via the cyclooxygenase pathway, and other cyclooxygenase activity.


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Santa Cruz Biotechnology, Inc.
200969
Santa Cruz Biotechnology, Inc.
sc-200969
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Properties for 12(S)-HHT

Molecular Weight:
280.4 g·mol−1
Boiling point:
78° C
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Safety & Transport Information

Risk Codes:
R11 - Highly flammable
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S16 - Keep away from sources of ignition - No smoking
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
Hazard Symbols:
F, Xi
Hazard symbol F Hazard symbol Xi
Storage temperature :
-20°C
RID/ADR certification :
UN 1170 3 / PG 2
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Alternative Distributors of [12(S)-HHT]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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MSDS:
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