HIP-B | CAS 227619-65-0 | Chemical-Suppliers

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C-S » Chemicals » hip-PX81007

Identification

HIP-B

CAS:

227619-65-0

EINECS:

Molecular Formula:

C₆H₈ N₂ O₄

MDL:

SMILES:

C1[C@H]2[C@@H]([C@H](N1)C(=O)O)ONC2=O

Synonym:

3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID ; HIP-B ; 2H-Pyrrolo[3,4-d]isoxazole-6-carboxylicacid, hexahydro-3-oxo-, (3aR,6R,6aR)-rel-

Description

HIP-B is a potent, non-competitive excitatory amino acid transporter (EAAT) blocker. HIP-B preferentially inhibits glutamate-induced [3H]D-aspartate release (IC₅₀ = 1.2 µM) rather than [3H]L-glutamate uptake (IC₅₀ = 16.9 µM). Moderately selective; displays no affinity for NMDA and metabotropic glutamate receptors, and low affinity for AMPA and kainate receptors (IC₅₀ values are 35 and 45 μM respectively).

Suppliers

Santa Cruz Biotechnology, Inc.

203599

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Prices & Availability

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Properties for HIP-B

Molecular Weight:

172.13872 g·mol−1

Solubility:

Soluble to 20 mM in Water

Safety & Transport Information

Storage temperature :

Store at +4°C

Alternative Distributors of [HIP-B]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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Mol File:

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MSDS:

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