H1-7 (histone H1 phosphorylation site), PKA Substrate | CAS 65189-70-0

Element: phosphorylation substrate histone site

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C-S » Chemicals » histone-phosphorylation-site-pka-substrate-PX66551

Identification

H1-7 (histone H1 phosphorylation site), PKA Substrate

CAS:

65189-70-0

EINECS:

Molecular Formula:

C₃₁H₅₈N₁₄O₉

MDL:

SMILES:

CC(C(=O)NC(CO)C(=O)NCC(=O)N1CCCC1C(=O)O)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)N

Synonym:

Description

H1-7 (histone H1 phosphorylation site), PKA Substrate is a synthetic peptide that acts as a pseudo substrate for PKA (cAMP-dependent protein kinase). This peptide was derived from the calf thymus histone H1 amino acid sequence about serine-38 and was used to research the reaction mechanism of the PKA catalytic subunit. H1-7 exhibits a greater absolute catalytic rate of phosphorylation than H1, an absolute Michaelis constant 40-fold greater than whole histone H1, but exhibits less affinity. Peptide sequence of H1-7: RRKASGP.

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Santa Cruz Biotechnology, Inc.

201152

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Properties for H1-7 (histone H1 phosphorylation site), PKA Substrate

Molecular Weight:

770.9 g·mol−1

Density:

1.54 g/cm³

Solubility:

Soluble in water.

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