HPI-4 | CAS 302803-72-1 | Chemical-Suppliers

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C-S » Chemicals » hpi-PX84158

Identification

HPI-4

CAS:

302803-72-1

EINECS:

Molecular Formula:

C₁₇H₉Cl₂N₃O₂

MDL:

MFCD01911757

SMILES:

C1=CC=C2C(=C1)C(=O)N/C(=C(C#N)/C(=O)C3=C(C=C(C=C3)Cl)Cl)/N2

Synonym:

Description

HPI-4 is a Hedgehog pathway inhibitor and ciliogenesis inhibitor. The Hedgehog (HH) signaling pathway is targeted for anti-cancer therapeutics and HPI-4 blocks Sonic hedgehog (Shh)-induced hedgehog pathway activation (IC₅₀ = 7 μM) downstream of Smo. It also inhibits cytoplasmic AAA+ ATPase dynein-dependent microtubule gliding and ATPase activity.

Suppliers

Santa Cruz Biotechnology, Inc.

358720

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HPI-4,Hedgehog Pathway Inhibitor 4

Excenen Pharmatech Co., Ltd.

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Prices & Availability

Data is processed

Properties for HPI-4

Molecular Weight:

358.18 g·mol−1

Solubility:

Soluble in DMSO (>20 mg/ml).

Safety & Transport Information

coming up soon

Alternative Distributors of [HPI-4]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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Mol File:

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MSDS:

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