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(1-hydroxy-2-(1h-imidazol-1-yl)-ethylidene)bisphosphonic acid

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Formula: C5H10N2O7P2
CAS: 118072-93-8

Identification

Structural Formula
(1-hydroxy-2-(1h-imidazol-1-yl)-ethylidene)bisphosphonic acid
CAS:
118072-93-8
EINECS:
Molecular Formula:
C5H10N2O7P2
MDL:
MFCD00867791
Synonym:
zol 446 ; phosphonic acid, (1-hydroxy-2-(1h-imidazol-1-yl)ethylidene)bis- ; zoledronicacid ; zometa ; bph 91 ; reclast ; zometa (novartis) ; zoledronic ; orazol ; zoledronate ; aclasta ; phosphonic acid,[1-hydroxy-2-(1h-imidazol-1-yl)ethylidene]bis- ; cgp-4244 ; [1-hydroxy-(1h-imidazol-1-yl)-phosphonoethyl] phosphonic acid monohydrate ; (1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl)phosphonic acid ; (1-hydroxy-2-imidazol-1-ylethylidene)diphosphonic acid ; 1-hydroxy-2-(1h-imidazol-1-yl)ethane-1,1-diyldiphosphonic acid ; cgp-42446 ; [1-hydroxy-2-(1h-imidazol-1-yl)ethylidene]bis phosphonic acid




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CM Fine Chemicals
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Chemieliva Pharmaceutical Co., Ltd.
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Aecochem Corp.
AC4201260
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Carbone Scientific Co., Ltd.
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Capot Chemical Co., Ltd.
14894
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Gihi Chemicals Co., Limited
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Medibro Corporation Limited
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Skyrun Industrial Co., Ltd.
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LGM Pharma
LP300900
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Pharmacore Co., Limited
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Pharmaffiliates Analytics & Synthetics Pvt. Limited
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Dayang Chem (Hangzhou) Co.,Ltd.
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Santa Cruz Biotechnology, Inc.
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Ambeed, Inc.
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CSNpharm, Inc.
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Finetech Industry Limited
FIL7503000
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Jiwan Pharmaceutical Technology Co., Ltd.
JPT12304920
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Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
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Xingrui Industry Co., Limited
XIL8703480
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Shandong Minglang Chemical Co., Ltd
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H&Z Industry Co.,Ltd
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Shandong SanYoung Industry Co., Ltd
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Zoledronic acid, anhydrous
Santa Cruz Biotechnology, Inc.
364663
[1-Hydroxy-2-(1H-imidazol-1-yl)-ethylidene]bisphosphonic acid
BLD Pharmatech Ltd
BP768623058
Phosphonic acid, [1-hydroxy-2-(1h-imidazol-1-yl)ethylidene]bis-
Angene International Limited
AGN-PC-04XYS4

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Properties for (1-hydroxy-2-(1h-imidazol-1-yl)-ethylidene)bisphosphonic acid

Molecular Weight:
290.10 g·mol−1
Density:
2.13 g/cm3
Melting point:
193-2040C (dec)
Boiling point:
764 °C at 760 mmHg
Flash point:
415.8 °C
Physical Description:
white crystalline powder
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:
R21/22 - Harmful in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Hazard Symbols:
Xi
Hazard symbol Xi
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Alternative Distributors of [(1-hydroxy-2-(1h-imidazol-1-yl)-ethylidene)bisphosphonic acid]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Daqing New Century Fine Chemical Co., Ltd | Heta Pharm & Chem Co., Ltd. | Kinfon Pharmaceutical and Chemical Service Co., Ltd. | Tai Hua Industries Co., Limited | Ningbo Zhengrun Chemicals Co., Ltd. Exp. Dept. | HuaiBei SanHe Developing Co., Ltd. | Shanghai Eagle Chemical Co., Ltd. | 3B Scientific Corporation | Aryl S.A. | Ningbo Highpharm Chem&Indu Co., Ltd. | Hangzhou Think Chemical Co., Ltd. | Afine Chemicals Limited | Xiang Ding Chemical International Co., Ltd | Qichun QiLong Chemical Co., Ltd. | Nantong Chem-Tech. (Group) Co., Ltd. | Vesino Industrial Co., Ltd. | Jiangsu Honghui Pharmaceutical Co., Ltd. | Pharmasi Chemicals Co., Ltd. | Taizhou Huading Chemical Co., Ltd. | Longschem Co., Ltd. | New Dragon Industrial Co., Ltd | Zhejiang Esun Chemical Co., Ltd. | Originchem Co., Ltd. | ShangHai Biochempartner Co., Ltd. | Shanghai Rainbow Chemicals Co., Ltd. | Evershine Chemical Co.,Ltd. | Hangzhou Hysen Pharma Co., Ltd. | Formax Chemicals Co., Ltd. | Long Island Pharmaceutical & Chemical Co. Ltd. | Jinan Wedo Industrial Co., Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Shanghai AOKChem Group Limited | Shanghai Chemsors chemicals Co., Ltd. | Suzhou Vosun Chemical Co.,Ltd. | Hangzhou Pharma & Chem Co. Ltd. | Lanospharma Laboratories Co., Ltd. | Shanghai Boyle Chemical Co., Ltd. | Wuxi Mizat Chemical Technology Co., Ltd. | Apichem Chemical Technology Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Jinan Great Chemical Co., Ltd. | Suzhou Sibian Chemical Technology Co., Ltd. | East Chemical Industry Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Discovery Fine Chemicals Limited | Cfm Oskar Tropitzsch GmbH | Yongyi Chemicals Group Co., Ltd. | Pharmfar Co., Ltd. | Aopharm | BOC Sciences | Jinan Haohua Industry Co., Ltd. | Shanxi Jinjin Chemical Co., Ltd. | Trademax Phamaceuticals & Chemicals Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | scienTEST | Clearsynth Canada INC. | Haihang Industry Co., Ltd.

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