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21(R)-Hydroxy Montelukast

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Formula: C35H36ClNO4S
CAS: 184763-26-6
search Element: montelukast hydroxy

Identification

Structural Formula
21(R)-Hydroxy Montelukast
CAS:
184763-26-6
EINECS:
Molecular Formula:
C35H36ClNO4S
MDL:
SMILES:
CC(C)(C1=CC=CC=C1[C@@H](C[C@H](C2=CC=CC(=C2)/C=C/C3=NC4=C(C=CC(=C4)Cl)C=C3)SCC5(CC5)CC(=O)O)O)O
Synonym:
21(r)-hydroxy montelukast ; [r-[r*,r*-(e)]]-1-[[[1-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxy-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]-cyclopropaneacetic aci ; [r-[r*,r*-(e)]]-1-[[[1-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxy-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]-cyclopropaneacetic acid ; montelukast m5b


Description

21(R)-Hydroxy Montelukast is an oxidative metabolite of the leukotriene LTD4 receptor antagonist Montelukast. This metabolite is hydroxylated at the benzylic 21-position of Monetlukast. Synthesis of 21(R)-Hydroxy Montelukast and the other oxidative metabolites of Montelukast has been reported. The diastereomer 21(S)-Hydroxy Montelukast has also been synthesized and described in the same report as 21(R)-Hydroxy Montelukast.


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Properties for 21(R)-Hydroxy Montelukast

Molecular Weight:
602.191 g·mol−1
Melting point:
76-81 °C
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Safety & Transport Information

Storage temperature :
Amber Vial, -20 °C Freezer, Under Inert Atmosphere
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Alternative Distributors of [21(R)-Hydroxy Montelukast]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Clearsynth Canada INC.

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Mol File:
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MSDS:
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