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4-Hydroxyphenylretinamide

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Formula: C26H33NO2
CAS: 65646-68-6
search Element: hydroxyphenylretinamide
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Identification

Structural Formula
4-Hydroxyphenylretinamide
CAS:
65646-68-6
EINECS:
Molecular Formula:
C26H33NO2
MDL:
MFCD00792674
SMILES:
CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)NC2=CC=C(C=C2)O)C)C
Synonym:
fenretinide(4-hpr) ; fenretinide ; fenretinide, >=98% ; retinamide ; 4-hydroxyphenylretinamide ; n-(4-hydroxyphenyl)-retinamid ; p-hydroxyphenylretinamide ; 4hpr ; hpr ; fenretinimide


Description

4-Hydroxyphenylretinamide (Fenretinide) is a synthetic retinoid analog of all trans retinoic acid, which displays antiproliferative effects on cultured human breast cancer cells. In addition, 4-Hydroxyphenylretinamide functions as a selective activator of RAR (retinoid receptors). Studies involving lymphoid and myeloid malignant cell lines indicate that 4-Hydroxyphenylretinamide can induce apoptosis and reduce cell growth. These studies suggest that 4-Hydroxyphenylretinamide and all trans retanoic acid may bind to two different receptors to induce apoptosis.


Suppliers

Santa Cruz Biotechnology, Inc.
200900
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Prices & Availability




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Properties for 4-Hydroxyphenylretinamide

Molecular Weight:
391.55 g·mol−1
Density:
1.08 g/cm3
Melting point:
162-163 °C
Boiling point:
597.61° C at 760 mmHg
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Safety & Transport Information

Risk Codes:
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R60 - May impair fertility
R61 - May cause harm to the unborn child
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S52 - Not recommended for interior use on large surface areas
S53 - Avoid exposure - obtain special instructions before use
Hazard Symbols:
T
Hazard symbol T
Storage temperature :
-20°C
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Alternative Distributors of [4-Hydroxyphenylretinamide]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences | Jinan Haohua Industry Co., Ltd.

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