2-Hydroxysaclofen is a sulphonic analogue of baclofen that acts as a selective GABAB antagonist. 2-Hydroxysaclofen functions as an antagonist by reducing the amplitude of the excitatory postsynaptic potentials (EPSPs) in hippocampal CA1 pyrimidal neurons. Studies suggest that 2-Hydroxysaclofen displaces baclofen from the binding site of GABAB, via reducing the apparent density and affinity of the binding sites. These studies indicate that 2-Hydroxysaclofen can possibly be a useful tool in determining the physiological significance of central baclofen receptors.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice S27 - Take off immediately all contaminated clothing S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Symbols:
C
Storage temperature :
2-8°C
RID/ADR certification :
UN 1759 8 / PG 3
x
Alternative Distributors of [2-Hydroxysaclofen]
Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
Element: 
Chemical-Suppliers.eu