(R)-Ibuprofen | CAS 51146-57-7 | Chemical-Suppliers

Element: ibuprofen

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C-S » Chemicals » ibuprofen-PX65444

Identification

(R)-Ibuprofen

CAS:

51146-57-7

EINECS:

Molecular Formula:

C₁₃H₁₈ O₂

MDL:

MFCD00069290

SMILES:

CC(C)CC1=CC=C(C=C1)[C@@H](C)C(O)=O

Synonym:

(-)-ibuprophen ; (r)-(-)-2-(4-isobutylphenyl)-propionic acid ; benzeneacetic acid, α-methyl-4-(2-methylpropyl)-, (r)- ; l-ibuprofen ; (r)-(-)-ibuprofen ; (-)-ibuprofen ; r-(-)-p-isobutylhydratropic acid ; (r)-2-(4-isobutylphenyl)propanoic acid ; (r)-ibuprofen ; benzeneaceticacid, a-methyl-4-(2-methylpropyl)-,(r)- ; benzeneacetic acid, a-methyl-4-(2-methylpropyl)-, (ar)- ; (-)-a-methyl-4-(2-methylpropyl)benzeneacetic acid ; (ar)-a-methyl-4-(2-methylpropyl)benzeneacetic acid

Description

(R)-Ibuprofen, a nonsteroidal antiinflammatory, is the less active enantiomer of ibuprofen, an inhibitor of Cox-1 and Cox-2. Most of the activity resides in (S)-ibuprofen. It has been observed that the inversion of R(-)-ibuprofen to the S(+) antipode occurs in rat liver but not in either serosal or mucosal sides of the small intestine. (R)-Ibuprofen's presence can be detected in urine through mass chromatography. A liquid-chromatographic assay has been used to study the pharmacokinetics of the (S)- and (R)-Ibuprofen forms in plasma.

Suppliers

Finetech Industry Limited

FIL6502600

Carbone Scientific Co., Ltd.

CS7282184

BOC Sciences

BS312936

Leap Chem Co., Ltd

LC4681404

Santa Cruz Biotechnology, Inc.

200625

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Prices & Availability

Data is processed

Properties for (R)-Ibuprofen

Molecular Weight:

206.28 g·mol−1

Density:

1.029 g/cm3

Melting point:

41-42°C

Boiling point:

319.6°C at 760 mmHg

Flash point:

216.7°C

Solubility:

Soluble in methanol, 0.1 M NaOH, dichloromethane, and ethyl acetate.

Safety & Transport Information

Storage temperature :

Refrigerator

Alternative Distributors of [(R)-Ibuprofen]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences | Clearsynth Canada INC.