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Imipramine N-oxide

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Formula: C19H24 N2 O
CAS: 6829-98-7
search Element: imipramine oxide

Identification

Structural Formula
Imipramine N-oxide
CAS:
6829-98-7
EINECS:
Molecular Formula:
C19H24 N2 O
MDL:
SMILES:
C[N+](C)(CCCN1C2=CC=CC=C2CCC3=CC=CC=C31)[O-]
Synonym:
10,11-dihydro-n,n-dimethyl-5h-dibenz(b,f)azepine-5-propanamine n-oxide ; 10,11-dihydro-n,n-dimethyl- ; 5h-dibenzb,fazepine-5-propanamine, 10,11-dihydro-n,n-dimethyl-, n-oxide ; ipno ; imipramine n-oxide ; 5h-dibenz[b,f]azepine,5-[3-(dimethylamino)propyl]-10,11-dihydro-, n-oxide (7ci,8ci) ; imipramine n-oxide monohydrate ; 5h-dibenz[b,f]azepine-5-propanamine,10,11-dihydro-n,n-dimethyl-, n-oxide ; imipraminoxide ; imipraminoxide monohydrate ; elepsin ; einecs 229-907-1 ; 5-[3-(dimethylamino)propyl]-10,11-dihydro-5h-dibenz[b,f]azepine5-oxide ; 19864-71-2 (hydrochloride)


Description

Imipramine N-oxide is the tertiary amine-oxidized form and a natural metabolite of the tricyclic serotonin/dopamine transport inhibitor Imipramine. FMO (Flavin-containing monooxygenase) enzymes are responsible for the oxidation of nucleophilic heteroatoms such as the tertiary amine of Imipramine, utilizing the bound cofactor flavin for redox coupling. Imipramine N-oxide can be used as a standard for investigating the presence and activity of FMO enzymes in relation to the FMO-mediated oxidation of Imipramine. Imipramine N-oxide is a substrate of FMO.


Suppliers

Santa Cruz Biotechnology, Inc.
200973
Dayang Chem (Hangzhou) Co.,Ltd.
DC11164464
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CAS equal suppliers

Imipramine N-Oxide Monohydrate
Pharmaffiliates Analytics & Synthetics Pvt. Limited
PA 09 09520

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Properties for Imipramine N-oxide

Molecular Weight:
296.41 g·mol−1
Melting point:
93-95°C
Boiling point:
583.50° C (Predicted)
Solubility:
Soluble in DMSO (30 mg/ml), ethanol (20 mg/ml), water (2 mg/ml warm), DMF, acetone, benzene, methanol, and ether.
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Safety & Transport Information

Hazard Classes:
6.1(b)
Storage temperature :
-20 °C Freezer
RID/ADR certification :
3249
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Alternative Distributors of [Imipramine N-oxide]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Clearsynth Canada INC.

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Downloads

Mol File:
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MSDS:
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