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Imiquimod

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Formula: C14H16N4
CAS: 99011-02-6
search Element: imiquimod
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Identification

Structural Formula
Imiquimod
CAS:
99011-02-6
EINECS:
Molecular Formula:
C14H16N4
MDL:
MFCD00866946
SMILES:
CC(C)CN1C=NC2=C1C1=C(C=CC=C1)N=C2N
Synonym:
aldara ; 4-amino- 1-isobutyl-1h-imidazo[4,5-c]quinoline ; imiquimod(aldara,r 837) ; imiquimod (aldara) ; imiquimod solution,100ppm ; 1-isobutyl-1h-imidazo[4,5-c]quinolin-4-amine ; imiquimod ; s-26308 ; r-837 ; imiquimod (200 mg)


Description

Imiquimod is a derivative of imidazoquinolinamine that inhibits angiogenesis and is an immune response modifier. Studies have reported that Imiquimod has the ability to downregulate metastasis and induce alpha-interferon (IFN-α). Additionally, Imiquimod is a TLR7 (toll-like receptor 7) agonist which induces plasmacytoid dendritic cell (pDC) maturation. Imiquimod acts on dendritic cells expressing TLR7, and induces an immune response. Nuclear factor-B helps mediate the activity of Imiquimod, and is involved in increasing chemokine and cytokine levels. The antiangiogenic property of Imiquimod has been shown to be mediated by IL-18. Research shows that Imiquimod can induce apoptosis in cancer cells. Also suggested to be an activator of caspase-3 and NFκB.


Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI6212484
+
Shandong Minglang Chemical Co., Ltd
SMC3151260
+
H&Z Industry Co.,Ltd
HIC180720
+
Shandong SanYoung Industry Co., Ltd
SSI3151260
+
Ambeed, Inc.
A161049
+
Gyma Laboratories Of America, Inc.
GLOA3061530
Suan Farma, Inc
SFI135540
+
Hangzhou Ocean Chemical Co., Ltd.
HOC2971188
+
Kingreat Chemistry Company Limited
KCCL3061530
+
Xiamen Equation Chemical Co.,Ltd
XECC2881440
+
CSNpharm, Inc.
CSN13134
Hangzhou Lingrui Chemical Co., Ltd.
HLC3151260
+
Wanko Chemical Co., Ltd.
WC216648
scienTEST - bioKEMIX GmbH
S-B225900
+
Hangzhou Ocean Chemical Co., Ltd.
HOC2971188
+
Finetech Industry Limited
FIL225900
+
Carbone Scientific Co., Ltd.
CS252756
+
CM Fine Chemicals
CFC153612
AK Scientific, Inc.
AS171513
+
Xingrui Industry Co., Limited
XIL2611044
+
BOC Sciences
BS108324
+
Amadis Chemical Company Limited
ACCL2791395
+
Leap Chem Co., Ltd
LC162486
+
Santa Cruz Biotechnology, Inc.
200385
Get Quick Quote

CAS equal suppliers

Aldara
Fox Chemicals GmbH
FC108324
Imiquimod, 99%
Alfa (A Johnson Matthey Company)
A4481344
1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
BLD Pharmatech Ltd
BP396011880
4-amino- 1-isobutyl-1h-imidazo(4,5-c)quinoline
Hangzhou J&H Chemical Co., Ltd.
HJC713028520
1H-imidazo[4,5-c]quinolin-4-amine, 1-(2-methylpropyl)-
Angene International Limited
AGN-PC-0JL20R

Prices & Availability




Data is processed


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Properties for Imiquimod

Molecular Weight:
240.3 g·mol−1
Density:
1.28 g/cm3 (Predicted)
Melting point:
292-294 °C
Boiling point:
456.71 °C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (4 mg/ml ,warming to 60 °C for 15 minutes) DMF (1.5 mg/ml) at 37 °C, and water (slightly soluble) at 37 °C. Insoluble in ethanol.
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Hazard Statements

GHS06

GHS06
Toxic
  • Acute toxicity (oral, dermal, inhalation), categories 1, 2, 3

Safety & Transport Information

Risk Codes:
R25 - Toxic if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S27 - Take off immediately all contaminated clothing
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Symbols:
T, Xi
Hazard symbol T Hazard symbol Xi
Storage temperature :
Store at +4 °C
RID/ADR certification :
UN 2811 6.1 / PG 3
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Alternative Distributors of [Imiquimod]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Finetech Industry Limited | BOC Sciences | Inter-Chemical Ltd. | Jinan Great Chemical Co., Ltd. | TCS INDUSTRY LTD. | Kinfon Pharmaceutical and Chemical Service Co., Ltd. | New Dragon Industrial Co., Ltd | Watson International Ltd | Ningbo Zhengrun Chemicals Co., Ltd. Exp. Dept. | Molekula GmbH | Hangzhou Think Chemical Co., Ltd. | scienTEST | Taizhou Creating Chemical Co., Ltd. | Jinan Haohua Industry Co., Ltd. | China Yangzhou Wandong Medical Co., Ltd. | Clearsynth Canada INC. | Suzhou Rovathin Pharmatech Co., Ltd | Discovery Fine Chemicals Limited | Suzhou Vosun Chemical Co.,Ltd. | Haihang Industry Co., Ltd. | Shanghai Boyle Chemical Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Shanghai Arbor Chemical Co., Ltd. | Tocopharm Co., Ltd. | East Chemical Industry Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Hubei Yuancheng Saichuang Tech.Co.,Ltd

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MSDS:
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