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Indole-3-carbinol

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Formula: C9H9NO
CAS: 700-06-1
search Element: carbinol indole

Identification

Structural Formula
Indole-3-carbinol
CAS:
700-06-1
EINECS:
211-836-2
Molecular Formula:
C9H9NO
MDL:
MFCD00005632
SMILES:
C1=CC=C2C(=C1)C(=CN2)CO
Synonym:
indole-3-carbinol ; i3c ; indol-3-carbinol ; indole-3-methanol ; 3-indolecarbinol ; akos ncg1-0099 ; 3-indolylmethanol ; indinol ; 3-indolamethanol ; 3-indolemethanol


Description

Indole-3-carbinol is a cell growth inhibitor that reversibly suppresses incorporation of [3H]thymidine in cells. This agent has been reported to induce G1 cell cycle arrest and block the expression of cyclin-dependent kinase 6. Additionally, Indole-3-carbinol displays the ability to inhibit endogenous retinoblastoma protein phosphorylation. Mechanistic studies suggest that in vitro this compound inhibits cell adhesion, migration, and invasion.


Suppliers

OPQ Chemical Co., Ltd
OC7142142
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI23469384
Shandong SanYoung Industry Co., Ltd
SSI11904760
Nantong Xindao Biotech Ltd
NXB8843536
Create Chemical Co., Ltd.
CC8502550
Shandong Minglang Chemical Co., Ltd
SMC11904760
Lori Industry Co., Ltd
LI7482244
Refine Chemical Co.,Ltd.
RCC8163264
Shandong Lanhai Industry Co.,Ltd.
SLIC11225610
H&Z Industry Co.,Ltd
HIC6802720
Unilong Industry Co.,Ltd
UIC8163264
Ambeed, Inc.
A135866
XD BIOCHEMS Ltd
XB5101530
Dudley Chemical Corp.
DCC7142856
Norchim S.A.S.
NS4761428
AIDP, Inc.
A340680
Ningbo Pangs Chem Co., Ltd.
NPC9183672
Suan Farma, Inc
SFI5102040
Arcadia Biotechnology
AB7142142
Richman Chemical Inc.,
RCI7482992
X´ian Taicheng Chem Co., Ltd
XTC9863944
Junwee Chemical Co., Ltd.
JC8502550
Hangzhou Zhongqi Chem Co., Ltd
HZC10204080
Sancai Industry Co.,Ltd.
SIC8163264
Arakato Development Ltd
AD7822346
Zouping Mingxing Chemical Co., Ltd.
ZMC11904760
Daming Changda Co., Ltd.
LLB01210
Aecochem Corp.
AC4761428
CSNpharm, Inc.
CSN10458
Hangzhou Keying Chem Co., Ltd.
HKC10204080
Hangzhou Lingrui Chemical Co., Ltd.
HLC11904760
Finetech Industry Limited
FIL8503400
CM Fine Chemicals
CFC5782312
Xingrui Industry Co., Limited
XIL9863944
Capot Chemical Co., Ltd.
7265
Zehao Industry Co., Ltd.
ZI8162448
Leap Chem Co., Ltd
LC6121836
Santa Cruz Biotechnology, Inc.
202662
Chemos GmbH & Co. KG
CC6802040
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HetCat
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Wanko Chemical Co., Ltd.
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Key Organics Limited
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Prices & Availability




Data is processed


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Properties for Indole-3-carbinol

Molecular Weight:
147.17 g·mol−1
Density:
1.27 g/cm3 (Predicted)
Melting point:
96-99 °C(lit.)
Boiling point:
360.6° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (≥29 mg/ml), ethanol (50 mg/ml), water (≥7 mg/ml), methanol, chloroform, benzene, and acetone. Insoluble in cold water.
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:
R36/38 - Irritating to eyes and skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
Hazard Symbols:
Xi
Hazard symbol Xi
Storage temperature :
2-8°C
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Alternative Distributors of [Indole-3-carbinol]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | Sabinsa Corporation | Biosynth AG | Fischer Chemicals AG | Rongkang Industry Co.,Ltd - (NSTU Chemicals Hanggzhou Co.,) | Nanjing R&M Fine Chemical Co., Ltd. | Hallochem Pharma Co., Ltd. | 3B Scientific Corporation | Shanghai Eagle Chemical Co., Ltd. | Hangzhou FST Pharmaceutical Co., Ltd. | Liyang Huibang Chemical Co., Ltd. | Nantong Chem-Tech. (Group) Co., Ltd. | Changzhou ODOC International Trade Co., Ltd. | Tianjin Pharmacn Medical Technology Co., Ltd. | Pharmasi Chemicals Co., Ltd. | Shaanxi Maxsun Trading Co., Ltd. | Laboratoires Plan SA | Donboo Amino Acid Co., Ltd. | Chemwill Asia Co.,Limited | ShangHai Biochempartner Co., Ltd. | Unispec Chemicals Co. | Chengdu Qiaofeng Technological Development Co., Ltd. | Bona Chemical Co., Limited | Shanghai AOKChem Group Limited | Shanghai Richem International Co., Ltd. | Share Chemical Co., Ltd. | Xi´an Union Pharmpro Co., Ltd. | Shanghai Brightol International Co., Ltd. | Hangzhou Pharma & Chem Co. Ltd. | Lanospharma Laboratories Co., Ltd. | Rosewell Industry Co., Ltd. | Win-Win Chemical Co., Limited | Junwee Chemical Co., Ltd. | Baisun Hongkong Import and Export Co., Ltd. | Jinan Great Chemical Co., Ltd. | Nantong Qihai Chemicals Co., Ltd. | Ruiyuan Group Limited | 3Way Pharm Inc. | Shanghai Insight Chemicals Co., Ltd. | Aakash Chemicals & Dye-Stuffs, Inc. | East Chemical Industry Co., Ltd. | Kairer Chengdu Pharmaceutical Co., Ltd. | All Right Chemical Co., Ltd. | Cfm Oskar Tropitzsch GmbH | Shanghai Arbor Chemical Co., Ltd. | Watson International Ltd | Pharmfar Co., Ltd. | Pangea Chemicals | BOC Sciences | Hubei Yuancheng Saichuang Tech.Co.,Ltd | Sciyu Biotech Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Pfaltz & Bauer, Inc. | Green Fine Chemical (Shanghai) Co., Ltd. | Hangzhou Neway Chemicals Co., Ltd. | Intatrade Chemicals GmbH | Clearsynth Canada INC.

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