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Kavain (+/-)

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Formula: C14H14O3
CAS: 500-64-1
search Element: kavain

Identification

Structural Formula
Kavain (+/-)
CAS:
500-64-1
EINECS:
Molecular Formula:
C14H14O3
MDL:
MFCD00270446
SMILES:
COC1=CC(=O)OC(C1)/C=C/C2=CC=CC=C2
Synonym:


Description

Kavain (+/-), a lipophilic kavapyrone, has been originally extracted from Piper methysticum. This compound has been shown to significantly antagonize dopamine depletion in murine striatal neurons. Additional studies report that Kavain (+/-) impairs vascular smooth muscle contraction via inhibition of Ca+ channels, causing relaxation in precontracted murine ileum, airways, and aortic rings. Furthermore, at high concentrations, this agent has been noted to display neurotoxic characteristics.


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Santa Cruz Biotechnology, Inc.
201077
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Properties for Kavain (+/-)

Molecular Weight:
230.3 g·mol−1
Density:
1.16 g/cm3 (Predicted)
Melting point:
105.5 °C
Boiling point:
432.64° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (>25 mg/mL), DMF (>25 mg/mL), and ethanol (5 mg/mL warm).
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Alternative Distributors of [Kavain (+/-)]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Downloads

Mol File:
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MSDS:
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