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Keratinocyte Differentiation Inducer

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Formula: C24H23N5O3
CAS: 863598-09-8

Identification

Structural Formula
Keratinocyte Differentiation Inducer
CAS:
863598-09-8
EINECS:
Molecular Formula:
C24H23N5O3
MDL:
SMILES:
COC1=CC(=CC(=C1OC)OC)NC2=NC=C3C=CN(C3=N2)C4=CC=CC(=C4)CCC#N
Synonym:


Description

Keratinocyte Differentiation Inducer cell-permeable pyrrolo-pyrimidone compound that acts as a potent, ATP-competitive inhibitor of casein kinase II (IC50 = 9 nM) and an effective inducer of normal human keratinocytes (NHEK) differentiation (EC50 = 100 nM). Also reported to interact, direcly or indirectly, with cellular TANK-binding Kinase 1 (TBK1) and NIMA-related kinase 9 (NEK9).


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Santa Cruz Biotechnology, Inc.
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Properties for Keratinocyte Differentiation Inducer

Molecular Weight:
429.5 g·mol−1
Solubility:
Soluble in ethanol, and DMSO.
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Safety & Transport Information

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Alternative Distributors of [Keratinocyte Differentiation Inducer]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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