Leu-pNA, Chromogenic Substrate | CAS 4178-93-2

Element: chromogenic substrate

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Identification

Leu-pNA, Chromogenic Substrate

CAS:

4178-93-2

EINECS:

224-047-3

Molecular Formula:

C₁₂H₁₇N₃O₃

MDL:

MFCD00063681

SMILES:

CC(C)CC(C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])N

Synonym:

h-l-leu-pna ; l-leucine p-nitroanilide ; pentanamide,2-amino-4-methyl-n-(4-nitrophenyl)-, (2s)- ; l-leucyl-4-nitroanilide ; leu-pna ; valeranilide,2-amino-4-methyl-4'-nitro-, l- (8ci) ; leucine-pna ; l-leucine-p-nitroaniline ; leucine p-nitroanilide ; pentanamide,2-amino-4-methyl-n-(4-nitrophenyl)-, (s)- ; (s)-pentanamid ; h-leu-pnaÂ·hcl ; h-leu-pna ; n-a-l-leucine p-nitroanilide ; l-leucine-4-nitroanilide ; n-l-leucyl-p-nitroanilide ; l-leucine-p-nitroanilide ; l-leucyl-p-nitroanilide ; l-leu-p-nitroanilide

Description

Leu-pNA, Chromogenic Substrate is a substrate for aminopeptidase, a zinc dependent enzyme that assists in the digestion of proteins. The compound has been used in an ELISA assay to detect biological functionality of chicken aminopeptidase produced by E. coli. The compound has also been used to characterize the native IRAP (placental leucine aminopeptidase). Leu-pNA, Chromogenic Substrate is documented for use with pure samples as well as cell extracts in vitro. Leu-pNA, Chromogenic Substrate is a substrate of CD13.

Suppliers

Santa Cruz Biotechnology, Inc.

201164

Dayang Chem (Hangzhou) Co.,Ltd.

DC279011160

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Prices & Availability

Data is processed

Properties for Leu-pNA, Chromogenic Substrate

Molecular Weight:

251.28 g·mol−1

Density:

1.226 g/cm3

Melting point:

88-90 °C

Boiling point:

454.5 °C at 760 mmHg

Flash point:

228.7 °C

Solubility:

Soluble in DMSO (>100 mM), and methanol (>25 mM).

Physical Description:

crystalline, colourless liquid

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:

R36 - Irritating to eyes
R43 - May cause sensitisation by skin contact

Safety Codes:

S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37 - Wear suitable protective clothing and gloves

Hazard Symbols: