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Levosimendan

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Formula: C14H12N6O
CAS: 141505-33-1
search Element: levosimendan
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Identification

Structural Formula
Levosimendan
CAS:
141505-33-1
EINECS:
Molecular Formula:
C14H12N6O
MDL:
MFCD00867135
SMILES:
CC1CC(=O)NN=C1C2=CC=C(C=C2)NN=C(C#N)C#N
Synonym:
levosimendanc14h12n60 ; r)-((4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazono) propanedintrile ; (r)-simendan ; or-1259 ; -2-[[4-(1?4?5?6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)19henyl]hydrazono]propandinitrile ; (r)-2-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl] hydrozono]pro ; simdax ; simda ; levosimendan ; [[4-[(4r)-1,4,5,6-terahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl]hydrazono]propanedinitrile


Description

Levosimendan is a Ca2+ sensitizer that increases contractile force of the myocardium by enhancing the sensitivity of myofilaments to calcium without increasing intracellular calcium concentration. Levosimendan has been shown to reduce circulating proinflammatory cytokine interleukin-6 and soluble apoptosis mediators. Levosimendan is an inhibitor of PDE.


Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI8283312
+
Lori Industry Co., Ltd
LI264792
+
Shandong Lanhai Industry Co.,Ltd.
SLIC3961980
+
XD BIOCHEMS Ltd
XB180540
+
Shandong SanYoung Industry Co., Ltd
SSI4201680
+
Nantong Xindao Biotech Ltd
NXB3121248
+
Ambeed, Inc.
A103792
+
JieJie Group Co., Ltd.
JG264792
+
Hangzhou Verychem Science & Technology Co., Ltd.
HVST5762880
+
Xiamen Equation Chemical Co.,Ltd
XECC3841920
+
Sancai Industry Co.,Ltd.
SIC2881152
+
Arakato Development Ltd
AD276828
+
Fox Chemicals GmbH
FC216648
+
CSNpharm, Inc.
CSN12524
Pharmacore Co., Limited
PL276828
Hefei Hirisun Pharmatech Co., Ltd
HR120409
+
AK Scientific, Inc.
AS228684
+
Simagchem Corporation
SC252756
+
Xingrui Industry Co., Limited
XIL3481392
+
Zehao Industry Co., Ltd.
ZI288864
+
BOC Sciences
BS144432
+
Leap Chem Co., Ltd
LC216648
+
Santa Cruz Biotechnology, Inc.
204792
Dayang Chem (Hangzhou) Co.,Ltd.
DC3721488
+
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CAS equal suppliers

(R)-N-(4-(4-Methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)carbonohydrazonoyl dicyanide
BLD Pharmatech Ltd
BP1674050220

Prices & Availability




Data is processed


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Properties for Levosimendan

Molecular Weight:
280.28 g·mol−1
Density:
~1.3 g/cm3 (Predicted)
Melting point:
216-219°C (dec.)
Solubility:
Soluble in water (<1 mg/ml), DMSO (56 mg/ml), methanol, and ethanol (<1 mg/ml).
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Safety & Transport Information

Risk Codes:
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
Safety Codes:
S36/37 - Wear suitable protective clothing and gloves
Hazard Symbols:
Xn
Hazard symbol Xn
Storage temperature :
-20°C Freezer
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Alternative Distributors of [Levosimendan]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Auspure Biotechnology Co., Ltd. | Hallochem Pharma Co., Ltd. | East Chemical Industry Co., Ltd. | 3B Scientific Corporation | Chongqing Ensky Chemical Co., Ltd. | Afine Chemicals Limited | Pharmasi Chemicals Co., Ltd. | Hangzhou Think Chemical Co., Ltd. | Kinfon Pharmaceutical and Chemical Service Co., Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Shanghai AOKChem Group Limited | Shanghai Chemsors chemicals Co., Ltd. | Shanghai Boyle Chemical Co., Ltd. | AOKBIO Co., Ltd. | Jinan Great Chemical Co., Ltd. | BOC Sciences | Jinan Haohua Industry Co., Ltd. | Clearsynth Canada INC. | Wanko Chemical Co., Ltd.

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MSDS:
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