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Lomustine

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Formula: C9H16ClN3O2
CAS: 13010-47-4
search Element: lomustine
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Identification

Structural Formula
Lomustine
CAS:
13010-47-4
EINECS:
235-859-2
Molecular Formula:
C9H16ClN3O2
MDL:
MFCD00012392
SMILES:
C1CCC(CC1)NC(=O)N(CCCl)N=O
Synonym:
rb1509 ; icig1109 ; belustine ; ccnu ; ceenu ; sri2200 ; cinu ; cecenu ; nsc79037 ; lomustin


Description

Lomustine is an alkylating nitrosourea compound that possesses antitumor activity similar to Carmustine causing DNA interstrand cross-linking. The compound is also a documented inhibitor of glutathione reductase, DLD(lipoamide dehydrogenase) and trypanothione reductase. Lomustine is a highly lipid soluble compound thus enabling it to cross the blood brain barrier and rapidly disperse in tissue. In A2870 cells, Lomustine has been shown to induce p53 expression.


Suppliers

H&Z Industry Co.,Ltd
HIC180720
+
Shandong Ench Chemical Co.,Ltd
SECC2701350
+
Shandong Minglang Chemical Co., Ltd
SMC3151260
+
Lori Industry Co., Ltd
LI198594
+
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI6212484
+
Xiamen Equation Chemical Co.,Ltd
XECC2881440
+
Sancai Industry Co.,Ltd.
SIC216864
+
CSNpharm, Inc.
CSN11325
Sigma-Aldrich International GmbH
SI288864
+
Finetech Industry Limited
FIL225900
+
AK Scientific, Inc.
AS171513
+
Xingrui Industry Co., Limited
XIL2611044
+
Leap Chem Co., Ltd
LC162486
+
Santa Cruz Biotechnology, Inc.
202697
Chemos GmbH & Co. KG
CC180540
+
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CAS equal suppliers

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Manchester Organics Limited
W24953
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Angene International Limited
AGN-PC-09ZN2M

Prices & Availability




Data is processed


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Properties for Lomustine

Molecular Weight:
233.7 g·mol−1
Density:
1.35 g/cm3
Melting point:
88-90
Boiling point:
354.07° C (Predicted)
Solubility:
Soluble in ethanol (47 mg/ml at 25° C), chloroform, water (<1 mg/ml at 25° C), DMSO (47 mg/ml at 25° C), and acetone.
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Hazard Statements

GHS06

GHS06
Toxic
  • Acute toxicity (oral, dermal, inhalation), categories 1, 2, 3

Safety & Transport Information

Risk Codes:
R25 - Toxic if swallowed
R45 - May cause cancer
Safety Codes:
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use
Hazard Classes:
6.1(a)
Hazard Symbols:
T
Hazard symbol T
Storage temperature :
-20°C
RID/ADR certification :
3249
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Alternative Distributors of [Lomustine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences | Inter-Chemical Ltd. | Jinan Great Chemical Co., Ltd. | Gihi Chemicals Co., Limited | Lanospharma Laboratories Co., Ltd. | Yangzhou Siyu Chemical Co., Ltd. | SYNCHEM OHG | Kinfon Pharmaceutical and Chemical Service Co., Ltd. | Xiang Ding Chemical International Co., Ltd | New Dragon Industrial Co., Ltd | 3B Scientific Corporation | Hangzhou Onicon Chemical Co., Ltd. | CCS. CHEM. Co., Ltd. | Hallochem Pharma Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Jiangsu Honghui Pharmaceutical Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Bepharm Ltd. | Shanghai AOKChem Group Limited | Zibo Panxin Pharmaceutical Co., Ltd. | Shanghai Richem International Co., Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Suzhou Vosun Chemical Co.,Ltd. | TRUST&WE Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Bichem Lab Co., Ltd. | East Chemical Industry Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Wanko Chemical Co., Ltd.

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