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Mabuterol

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Formula: C13H18ClF3N2O
CAS: 56341-08-3
search Element: mabuterol

Identification

Structural Formula
Mabuterol
CAS:
56341-08-3
EINECS:
Molecular Formula:
C13H18ClF3N2O
MDL:
MFCD00867035
SMILES:
CC(C)(C)NCC(C1=CC(=C(C(=C1)Cl)N)C(F)(F)F)O
Synonym:
pb 868cl ; ambuterol ; mabuterol ; benzenemethanol, 4-amino-3-chloro-a-[[(1,1-dimethylethyl)amino]methyl]-5-(trifluoromethyl)- (9ci) ; 1-[4-azanyl-3-chloro-5-(trifluoromethyl)phenyl]-2-(tert-butylamino)ethanol ; 4-amino-3-chloro-α-[[(1,1-dimethylethyl)amino]methyl]-5-(trifluoromethyl)benzenemethanol ; 4-amino-α-[(tert-butylamino)methyl]-5-(trifluoromethyl)benzene-methanol ; 4-amino-3-chloro-alpha-[[(tert-butyl)amino]methyl]-5-(trifluoromethyl)benzenemethanol hydrochloride


Description

Mabuterol is a long acting β2-adrenergic agonist which stimulates adenylyl cyclase activity and the closing of calcium channels. Studies indicate that the R enantiomer of Mabuterol is more potent than the S enantiomer. In addition, the half-life is longer in the R enantiomer than the S. Studies conducted on rats and dogs show that Mabuterol acts as a bronchodilator. These studies demonstrated that at high concentrations Mabuterol can also antagonize &beta1 adrenoceptors in guinea pigs.


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Properties for Mabuterol

Molecular Weight:
310.74 g·mol−1
Density:
1.28 g/cm3 (Predicted)
Melting point:
85-87 °C C
Boiling point:
375.86° C at 760 mmHg (Predicted)
Solubility:
Soluble in chloroform, methanol, and Partly Miscible in water.
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Safety & Transport Information

Storage temperature :
Hygroscopic, -20 °C Freezer, Under Inert Atmosphere
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Alternative Distributors of [Mabuterol]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Ningbo Inno Pharmchem Co. Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Shanghai AOKChem Group Limited | Shanghai Elittes Organics Co., Ltd. | Kinfon Pharmaceutical and Chemical Service Co., Ltd. | BOC Sciences | Jinan Haohua Industry Co., Ltd. | Clearsynth Canada INC.

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MSDS:
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