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4-Methylumbelliferyl sulfate, potassium salt

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Formula: C10H7KO6S
CAS: 15220-11-8

Identification

Structural Formula
4-Methylumbelliferyl sulfate, potassium salt
CAS:
15220-11-8
EINECS:
Molecular Formula:
C10H7KO6S
MDL:
MFCD00016970
SMILES:
CC1=CC(=O)OC2=C1C=CC(=C2)OS(=O)(=O)[O-].[K+]
Synonym:
potassium 4-methylumbelliferonesulfate ; 4-methylumbelliferyl sulfate potassium ; potassium 4-methylumbelliferyl sulfate ; 4-methylumbelliferone sulfate potassium salt ; potassium 4-methylumbelliferone sulfate ; 2h-1-benzopyran-2-one,4-methyl-7-(sulfooxy)-, potassium salt (9ci) ; potassium(4-methyl-2-oxo-2h-chromen-7-yl)sulfate ; 4-mu-sulfate k ; 4-methylumbelliferyl sulphate potassium salt ; 4-mus ; coumarin, 7-hydroxy-4-methyl-,hydrogen sulfate potassium salt (8ci) ; einecs 239-272-2 ; 4-methylumbelliferyl sulfate potassium salt ; 4-methylumberiferryl sulfate potassium salt ; 2h-1-benzopyran-2-one,4-methyl-7-(sulfooxy)-, potassium salt ; potassium 4-methylumbelliferyl sulfate


Description

4-Methylumbelliferyl sulfate, potassium salt is a coumarin derivative and highly sensitive fluorescent substrate for monitoring aryl sulfatase activity. This substrate has been used in the discovery of tyrosine sulfotransferase inhibitors, particularly in P-selectin glycoprotein ligand-1 binding. This compound is virtually non-fluorescent until cleavage by sulfatase enzymes, then emits blue fluorescence (450 nm) with excitation at 360 nm. Use of this compound in high-throughput fluorescence based screening led to the discovery of several potent beta-arylsulfotransferase IV (beta-AST-IV) inhibitors.


Suppliers

Santa Cruz Biotechnology, Inc.
206917
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CAS equal suppliers

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4-Methylumbelliferyl sulfate potassium salt, 98%
Alfa (A Johnson Matthey Company)
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Prices & Availability




Data is processed


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Properties for 4-Methylumbelliferyl sulfate, potassium salt

Molecular Weight:
256.2319 g·mol−1
Density:
1.59 g/cm3
Melting point:
287-290 °C
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Safety & Transport Information

Safety Codes:
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
Storage temperature :
2-8°C
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Alternative Distributors of [4-Methylumbelliferyl sulfate, potassium salt]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Biosynth AG | Alfa Aesar, a Johnson Matthey Company | Pfaltz & Bauer, Inc.

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MSDS:
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