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Mirtazapine

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Formula: C17H19N3
CAS: 61337-67-5
search Element: mirtazapine

Identification

Structural Formula
Mirtazapine
CAS:
61337-67-5
EINECS:
Molecular Formula:
C17H19N3
MDL:
SMILES:
CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4
Synonym:
6-azamianserin ; remergon ; remeron ; org-3770 ; mepirzepine ; mirtazepine ; mitazapine ; mirtazanine ; mirtazapine ; zispin


Description

Mirtazapine is a potent SR-2 (pKi 8.05) and SR-3 (pKi 8.1) antagonist in addition to being a moderately potent α2 adrenoceptor (pKi 6.9) and histamine H1 receptor antagonist (pKi 9.3). Mirtazapine has been observed to inhibit α2 adrenergic autoreceptors, enhancing noradrenaline release, as well as showing weak affinity for monoamine transporters. Mirtazapine has also been documented to increase hippocampal noradrenaline and serotonin.


Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI7593036
H&Z Industry Co.,Ltd
HIC220880
Shandong SanYoung Industry Co., Ltd
SSI3851540
Hangzhou Verychem Science & Technology Co., Ltd.
HVST5282640
Xiamen Equation Chemical Co.,Ltd
XECC3521760
Aecochem Corp.
AC154462
Wanko Chemical Co., Ltd.
WC264792
Sigma-Aldrich International GmbH
SI3521056
Finetech Industry Limited
FIL2751100
Carbone Scientific Co., Ltd.
CS308924
Xingrui Industry Co., Limited
XIL3191276
Capot Chemical Co., Ltd.
22104
Leap Chem Co., Ltd
LC198594
Santa Cruz Biotechnology, Inc.
204088
Dayang Chem (Hangzhou) Co.,Ltd.
DC3411364
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Prices & Availability




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Properties for Mirtazapine

Molecular Weight:
265.35 g·mol−1
Melting point:
114-116 °C
Solubility:
DMSO: ~8 mg/mL, soluble
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
  • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization
GHS08

GHS08
Health hazard
  • Respiratory sensitization, category 1
  • Germ cell mutagenicity, categories 1A, 1B, 2
  • Carcinogenicity, categories 1A, 1B, 2
  • Reproductive toxicity, categories 1A, 1B, 2
  • Specific target organ toxicity following single exposure, categories 1, 2
  • Specific target organ toxicity following repeated exposure, categories 1, 2
  • Aspiration hazard, categories 1, 2
GHS09

GHS09
Environmental hazard
  • Acute hazards to the aquatic environment, category 1
  • Chronic hazards to the aquatic environment, categories 1, 2
  • Environmental toxicity, categories 1, 2

Safety & Transport Information

Risk Codes:
R11 - Highly flammable
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed
Safety Codes:
S16 - Keep away from sources of ignition - No smoking
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S7 - Keep container tightly closed
Hazard Symbols:
F, T
Hazard symbol T Hazard symbol F
Storage temperature :
2-8 °C
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Alternative Distributors of [Mirtazapine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Kinfon Pharmaceutical and Chemical Service Co., Ltd. | Matrix Laboratories Limited | HuaiBei SanHe Developing Co., Ltd. | Hallochem Pharma Co., Ltd. | Shanghai Eagle Chemical Co., Ltd. | 3B Scientific Corporation | Hangzhou Think Chemical Co., Ltd. | Changsha Huajia Chemical Science Co., Ltd. | Aryl S.A. | Charna Chemicals Ltd. | Qichun QiLong Chemical Co., Ltd. | Nantong Chem-Tech. (Group) Co., Ltd. | China Yangzhou Wandong Medical Co., Ltd. | Synfine Research Inc. | New Dragon Industrial Co., Ltd | Shanghai AOKChem Group Limited | Suzhou Rovathin Pharmatech Co., Ltd | TCS INDUSTRY LTD. | Hangzhou Pharma & Chem Co. Ltd. | Lanospharma Laboratories Co., Ltd. | Yichang Humanwell Pharmaceutical Co., Ltd. | Jinan Great Chemical Co., Ltd. | Jinjiangchem Corporation | ShangHai Biochempartner Co., Ltd. | East Chemical Industry Co., Ltd. | Shanghai Witofly Chemical Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | King Tang Chemical Group Industry Co., Ltd. | Watson International Ltd | Yongyi Chemicals Group Co., Ltd. | BOC Sciences | Hubei Yuancheng Saichuang Tech.Co.,Ltd | Jinan Haohua Industry Co., Ltd. | Finetech Industry Limited | Xiamen Hisunny Chemical Co., Ltd. | Trademax Phamaceuticals & Chemicals Co., Ltd. | Clearsynth Canada INC.

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