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Molsidomine

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Formula: C9H14N4O4
CAS: 25717-80-0
search Element: molsidomine

Identification

Structural Formula
Molsidomine
CAS:
25717-80-0
EINECS:
247-207-4
Molecular Formula:
C9H14N4O4
MDL:
MFCD00869301
SMILES:
CCOC(=NC1=C[N+](=NO1)N2CCOCC2)[O-]
Synonym:
sin-10 ; morial ; coruno ; cas 276 ; corvasal ; corvaton ; corraton ; motazomin ; molsidolat ; sydnopharm


Description

Molsidomine is a long-lasting, NO releasing vasodilator. It requires hepatic metabolism to be active, but causes no pharmacological tolerance. It is a useful antianginal. It has been shown to be enzymatically metabolized SIN-1 by the liver, then readily converted to active metabolite SIN-1A. It relaxes smooth muscle by activating GCS (soluble guanylate cyclase) which leads to increased cGMP formation. When administered after or prior to cardiac insult, it has been reported to reduce myocardial infarct size.


Suppliers

Nantong Xindao Biotech Ltd
NXB2861144
Ambeed, Inc.
A335612
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI7593036
IPOCHEM Sp. z o.o.
ISZO198990
Xiamen Equation Chemical Co.,Ltd
XECC3521760
Sancai Industry Co.,Ltd.
SIC2641056
CSNpharm, Inc.
CSN11463
Carbone Scientific Co., Ltd.
CS308924
AK Scientific, Inc.
AS209627
Simagchem Corporation
SC231693
Xingrui Industry Co., Limited
XIL3191276
Zehao Industry Co., Ltd.
ZI264792
Leap Chem Co., Ltd
LC198594
Santa Cruz Biotechnology, Inc.
200337
Dayang Chem (Hangzhou) Co.,Ltd.
DC3411364
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Properties for Molsidomine

Molecular Weight:
242.23 g·mol−1
Melting point:
140-141°C
Solubility:
Soluble in methanol, ethanol (35 mg/ml), DMSO (70 mg/ml), DMF (13 mg/ml), PBS (pH 7.2) (9 mg/ml), and water (15 mg/ml) at 25° C.
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Safety & Transport Information

Risk Codes:
R22 - Harmful if swallowed
Safety Codes:
S36 - Wear suitable protective clothing
Hazard Symbols:
Xn
Hazard symbol Xn
Storage temperature :
2-8°C
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Alternative Distributors of [Molsidomine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

CCS. CHEM. Co., Ltd. | Hallochem Pharma Co., Ltd. | Xiang Ding Chemical International Co., Ltd | Nantong Chem-Tech. (Group) Co., Ltd. | Changzhou Sinly Pharmchem Co., Ltd. | Hangzhou Hysen Pharma Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Jinan Great Chemical Co., Ltd. | East Chemical Industry Co., Ltd. | Yongyi Chemicals Group Co., Ltd. | Watson International Ltd | Jinan Haohua Industry Co., Ltd. | Trademax Phamaceuticals & Chemicals Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Gihi Chemicals Co., Limited | Clearsynth Canada INC.

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