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Nadifloxacin

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Formula: C19H21FN2O4
CAS: 124858-35-1
search Element: nadifloxacin

Identification

Structural Formula
Nadifloxacin
CAS:
124858-35-1
EINECS:
Molecular Formula:
C19H21FN2O4
MDL:
MFCD00865081
SMILES:
CC1CCC2=C3N1C=C(C(=O)C3=CC(=C2N4CCC(CC4)O)F)C(=O)O
Synonym:
nadifiloxacin ; acuati ; ndfx ; acuatim ; opc7251 ; nadiroxisan ; nadifloxacinapi ; jinofloxacin ; nadifloxacin ; nadiflo


Description

Nadifloxacin is a cell-permeable, synthetic, broad-spectrum fluoroquinolone antibiotic that inhibits the growth of both gram-positive and gram-negative microbes. Studies suggest that the mechanism of inhibition occurs by interfering with DNA replication. Specifically Nadifloxacin suppresses gram-positive bacterial growth by targeting topoisomerase IV and suppresses gram-negative bacteria by inhibiting Topo II (DNA gyrase), which both function to relax postive supercoils before DNA replication. Furthermore, Nadifloxacin can decrease superoxide radical anions such as O2- and OH-, produced by neutrophils.


Suppliers

Nantong Xindao Biotech Ltd
NXB3121248
Ambeed, Inc.
A140688
Aozeal Certified Standards (AOCS), Inc.
N0029.00
Chenghui Pharmaceutical Group Zone
CPGZ4082040
Xiamen Equation Chemical Co.,Ltd
XECC3841920
CSNpharm, Inc.
CSN16703
Pharmacore Co., Limited
PL276828
Hefei Hirisun Pharmatech Co., Ltd
HR131131
CM Fine Chemicals
CFC204816
AK Scientific, Inc.
AS228684
Simagchem Corporation
SC252756
Xingrui Industry Co., Limited
XIL3481392
Leap Chem Co., Ltd
LC216648
Santa Cruz Biotechnology, Inc.
202723
Dayang Chem (Hangzhou) Co.,Ltd.
DC3721488
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Prices & Availability




Data is processed


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Properties for Nadifloxacin

Molecular Weight:
360.38 g·mol−1
Density:
~1.5 g/cm3 (Predicted)
Melting point:
245-2470C (dec)
Boiling point:
~624.9° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (20 mg/ml at 25° C), water (<1 mg/ml at 25° C), and ethanol (<1 mg/ml at 25° C).
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Safety & Transport Information

Storage temperature :
-20°C Freezer
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Alternative Distributors of [Nadifloxacin]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

CCS. CHEM. Co., Ltd. | 3B Scientific Corporation | Hangzhou Think Chemical Co., Ltd. | Xiang Ding Chemical International Co., Ltd | New Dragon Industrial Co., Ltd | Discovery Fine Chemicals Limited | Chengdu Qiaofeng Technological Development Co., Ltd. | Shanghai AOKChem Group Limited | AOKBIO Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Jinan Great Chemical Co., Ltd. | East Chemical Industry Co., Ltd. | Watson International Ltd | Aopharm | BOC Sciences | Jinan Haohua Industry Co., Ltd. | Suzhou Vosun Chemical Co.,Ltd. | Beijing Mediking Biopharm Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Gihi Chemicals Co., Limited | Clearsynth Canada INC.

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