Nifedipine | CAS 21829-25-4 | Chemical-Suppliers

Element: nifedipine

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C-S » Chemicals » nifedipine-PX64478

Identification

Nifedipine

CAS:

21829-25-4

EINECS:

244-598-3

Molecular Formula:

C₁₇H₁₈N₂O₆

MDL:

MFCD00057326

SMILES:

CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC

Synonym:

sepamit ; oxcord ; pidilat ; bay1040 ; anifed ; orix ; nifedin ; adalat ; nifelan ; zenusin

Description

Nifedipine is a selective hypertensive calcium channel protein inhibitor which targets L-type voltage-sensitive calcium channels. Nifedipine is a vasodilator that is selective for inotropic over chronotropic cardiac effects. It has also been shown to induce apoptosis in human glioblastoma cells and inhibit advanced glycation end product-induced mesangial cell damage in vitro. Additionally, nifedipine has been suggested to work as an antioxidant and antiinflammatory agent against AGEs in tubular cells by suppressing RAGE expression via PPAR-γ activation.

Suppliers

Aozeal Certified Standards (AOCS), Inc.

N0002.00

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI6902760

Shandong Ench Chemical Co.,Ltd

SECC3001500

H&Z Industry Co.,Ltd

HIC200800

Krada CPS Industry S.L

KCIS2201100

AXO Industry SA

AIS150600

Jinan Honestpharm Co., Ltd

JH260780

Xiamen Equation Chemical Co.,Ltd

XECC3201600

Hainan Zhongxin Chemical Co., Ltd.

HZC3401360

Aecochem Corp.

AC140420

CSNpharm, Inc.

CSN11555

Wanko Chemical Co., Ltd.

WC240720

Sigma-Aldrich International GmbH

SI320960

scienTEST - bioKEMIX GmbH

S-B2501000

Hangzhou Ocean Chemical Co., Ltd.

HOC3301320

Hefei Hirisun Pharmatech Co., Ltd

HR010697

AK Scientific, Inc.

AS190570

Xingrui Industry Co., Limited

XIL2901160

Leap Chem Co., Ltd

LC180540

Santa Cruz Biotechnology, Inc.

3589

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CAS equal suppliers

Nifedipinum

Autech Industry Co.,Limited

AIC2971188

Nifedipine-d4

Salsbury Chemicals, Inc.

SC312936

Nifedipine, 98%

Alfa (A Johnson Matthey Company)

A4801440

3,5-Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Salsbury Chemicals, Inc.

SC1360840824

3,5-Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

BLD Pharmatech Ltd

BP1020630618

1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester

Salsbury Chemicals, Inc.

SC1879256376

1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester

Gihi Chemicals Co., Limited

GCL2114184564

Prices & Availability

Data is processed

Properties for Nifedipine

Molecular Weight:

346.34 g·mol−1

Melting point:

171-175 °C

Solubility:

DMSO: soluble

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:

R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Classes:

irritant

Hazard Symbols:

Xn, Xi

Storage temperature :

2-8°C

Alternative Distributors of [Nifedipine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified