Nimesulide | CAS 51803-78-2 | Chemical-Suppliers

Element: nimesulide

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C-S » Chemicals » nimesulide-PX66377

Identification

Nimesulide

CAS:

51803-78-2

EINECS:

257-431-4

Molecular Formula:

C₁₃H₁₂N₂O₅S

MDL:

MFCD00079470

SMILES:

CS(=O)(=O)NC1=C(OC2=CC=CC=C2)C=C(C=C1)[N+]([O-])=O

Synonym:

nide ; aulin ; r-805 ; lizepat ; nisulid ; nidol ; aufin ; nimed ; nisuli ; mesulid

Description

Nimesulide is an anti-inflammatory small molecule inhibitor of Cox (cyclooxygenase). Nimesulide shows selectivity for Cox-2 over Cox-1. Reports have suggested that increased Cox-2 expression may present a survival advantage to cells by inhibiting apoptosis and changing cellular adhesions to the extracellular matrix, and Nimesulide is demonstrated to suppress azoxymethane-induced carcinogenesis.

Suppliers

Ambeed, Inc.

A370794

Aozeal Certified Standards (AOCS), Inc.

N0003.00

Krada CPS Industry S.L

KCIS2201100

CellMark AB

CA110330

X´ian Taicheng Chem Co., Ltd

XTC2901160

Xiamen Equation Chemical Co.,Ltd

XECC3201600

Aecochem Corp.

AC140420

CSNpharm, Inc.

CSN11614

Sigma-Aldrich International GmbH

SI320960

Finetech Industry Limited

FIL2501000

Hefei Hirisun Pharmatech Co., Ltd

HR011995

CM Fine Chemicals

CFC170680

AK Scientific, Inc.

AS190570

Simagchem Corporation

SC210630

Xingrui Industry Co., Limited

XIL2901160

Zehao Industry Co., Ltd.

ZI240720

Leap Chem Co., Ltd

LC180540

Santa Cruz Biotechnology, Inc.

200623

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CAS equal suppliers

N-(4-Nitro-2-phenoxyphenyl)methane sulfonamide

BLD Pharmatech Ltd

BP414012420

Prices & Availability

Data is processed

Properties for Nimesulide

Molecular Weight:

308.31 g·mol−1

Density:

1.45 g/cm³

Melting point:

140-146 °C

Boiling point:

442.03° C at 760 mmHg

Solubility:

Soluble in water (<50 µg/ml), 1:10 DMSO:PBS (pH 7.2) (<200 µg/ml), ethanol (1 mg/ml), DMSO (15 mg/ml), DMF (15 mg/ml), chloroform, dichloromethane, acetone (freely soluble), and 1N NaOH.

Hazard Statements

GHS06
Toxic

Acute toxicity (oral, dermal, inhalation), categories 1, 2, 3

Safety & Transport Information

Risk Codes:

R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Symbols:

Xn, Xi

Storage temperature :

2-8°C

RID/ADR certification :

UN 2811 6.1 / PG 3

Alternative Distributors of [Nimesulide]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified