N G-Nitro-L-arginine | CAS 2149-70-4

Element: arginine nitro

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C-S » Chemicals » nitro-arginine-PX73489

Identification

N G-Nitro-L-arginine

CAS:

2149-70-4

EINECS:

218-418-9

Molecular Formula:

C₆H₁₃N₅O₄

MDL:

MFCD00007033

SMILES:

C(C[C@@H](C(=O)O)N)CN=C(N)N[N+](=O)[O-]

Synonym:

h-arg(no2)-oh ; l-na, l-nna ; nsc 53662 ; nϖ ; ng-no2-l-arg ; arg(no2) ; l-nna ; l-no2arg ; l-na ; l-noarg

Description

N G-Nitro-L-arginine displays potent inhibition of NOS with selectivity for NOS1 and NOS3 over NOS2. It has been observed to inhibit endothelial nitric oxide biosynthesis and decrease radical generation of peroxynitrite ions. Other inhibitory effects demonstrated in experiments include blocking brady-kinin-induced relaxation in dog coronary artery strips and suppressing morphine tolerance in mice. N G-Nitro-L-arginine causes significant vasoconstriction and is utilized in studying nitric oxide as a neuronal messenger.

Suppliers

Santa Cruz Biotechnology, Inc.

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Prices & Availability

Data is processed

Properties for N G-Nitro-L-arginine

Molecular Weight:

219.2 g·mol−1

Density:

1.66 g/cm³ (Predicted)

Melting point:

257 °C (dec.)(lit.)

Boiling point:

462.43° C at 760 mmHg (Predicted)

Safety & Transport Information

Risk Codes:

R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Classes:

irritant

Hazard Symbols: