Noscapine hydrochloride | CAS 912-60-7

Element: hydrochloride noscapine

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C-S » Chemicals » noscapine-hydrochloride-PX69373

Identification

Noscapine hydrochloride

CAS:

912-60-7

EINECS:

213-014-9

Molecular Formula:

C₂₂H₂₄ClNO₇

MDL:

MFCD00082546

SMILES:

CN1CCC2=CC3=C(C(=C2[C@@H]1[C@H]4C5=C(C(=C(C=C5)OC)OC)C(=O)O4)OC)OCO3.Cl

Synonym:

lyobexhydrochloride ; coscopinhydrochloride ; noscapine base / hcl ; nectadonhydrochloride ; opianhydrochloride ; noscapinehcl ; capvalhydrochloride ; vadebexhydrochloride ; nsc5366hydrochloride ; longatinhydrochloride

Description

Noscapine hydrochloride is the hydrochloride form of Noscapine. Noscapine is an opioid alkaloid with several actions. Antagonist at Bradykinin B Receptor (bradykinin receptors) (pA2 = 6.68), inhibits carbachol-stimulated phosphoinositol turnover and enhances forskolin-stimulated cAMP increases in CNS tissues. Additionally Noscapine binds to tubulin, arrests cells in mitosis and induces apoptosis. Blocks proliferation of human leukemia and multiple myeloma cells. Furthermore, Noscapine modulates IKK activation, suppressing the NF-κB signaling pathway. Exhibits anti-inflammatory activity. Noscapine hydrochloride is an inhibitor of Tubulin.

Suppliers

Sigma-Aldrich International GmbH

SI14724416

Leap Chem Co., Ltd

LC8282484

Santa Cruz Biotechnology, Inc.

203650

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CAS equal suppliers

NOSCAPINE HCL

DKSH International AG

DIA5462184

Noscapine Hydrochloride Hydrate

TCI Chemicals (India) Pvt. Ltd.

N0963

Prices & Availability

Data is processed

Properties for Noscapine hydrochloride

Molecular Weight:

449.88 g·mol−1

Melting point:

221-223 °C(lit.)

Solubility:

Soluble in water, and 1eq. HCl (50 mM).

Safety & Transport Information

Risk Codes:

R22 - Harmful if swallowed

Safety Codes:

S36 - Wear suitable protective clothing

Hazard Classes:

6.1(b)

Hazard Symbols:

Xn, Xi

Storage temperature :

2-8°C

RID/ADR certification :

1544

Alternative Distributors of [Noscapine hydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

DKSH International AG | BOC Sciences | Jinan Great Chemical Co., Ltd. | Nantong Chem-Tech. (Group) Co., Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd.

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