n-Octyl-beta-D-glucopyranoside ultra-pure, 98%

Non-ionic, dialysable detergent for the solubilization and isolation of membrane proteins. Has been shown to increase the resolution of proteins in proteomics analysis. 1. Aveldano M.I., Diaz R.S., Regueiro P., Monreal J., Solubilization of myelin membranes by detergents. J. Neurochem. 1991, 57, 250-7. 2. Fanger B.O., Adaptation of the Bradford protein assay to membrane-bound proteins by solubilizing in glucopyranoside detergents. Anal. Biochem. 1987, 162, 11-7. 3. Gould R.J., Ginsberg B.H., Spector A.A., Effects of Octyl beta-glucoside on insulin binding to solubilized membrane receptors. Biochemistry 1981, 20, 6776-81. 4. Hallden G., Andersson U., Hed J., Johansson S.G., A new membrane permeabilization method for the detection of intracellular antigens by flow cytometry. J. Immunol. Methods 1989, 124, 103-9. 5. Jackson M.L., Schmidt C.F., Lichtenberg D., Litman B.J., Albert A.D., Solubilization of phosphatidylcholine bilayers by octyl glucoside. Biochemistry 1982, 21, 4576-82. 6. Lopez M.F., Proteome analysis. I. Gene products are where the biological action is. J. Chromatogr. B. Biomed. Sci. Appl. 1999, 722, 191-202. 7. Mimms L.T., Zampighi G., Nozaki Y., Tanford C., Reynolds J.A., Phospholipid vesicle formation and transmembrane protein incorporation using octyl glucoside. Biochemistry 1981, 20, 833-40. 8. Yoshida M., Suzuki A., Yamamoto H., Noguchi S., Mizuno Y., Ozawa E., Dissociation of the complex of dystrophin and its associated proteins into several unique groups by n-Octyl-beta-D-glucoside. Eur. J. Biochem. 1994, 222, 1055-61.