halochondrine a, potassium salt ; okadaic acid, potassium salt, 98+% ; okadaic acid potassium ; okadaic acid potassium salt from prorocentrum concavum ; 9,10-deepithio-9,10-didehydroacanthifolicin, potassium salt ; okadaic acid potassium salt ; 9,10-deepithio-9,10-didehydroacanthiofolicin ; okadaic acid potassium salt 98% ; okadaic acid potassium salt, prorocentrum concavum ; halochondrine a
Description
Okadaic Acid, Potassium Salt is a water-soluble analog of Okadaic Acid, isolated from cultured Prorocentrum concavum. The salt form is generated in aqueous potassium hydroxide methanol solution. The compound is a potent inhibitor of serine/threonine-specific protein phosphatases PP1, PP2A, 5534, PP2C and endogenous phosphatase smooth muscle myosin at IC50 of 10-15 nM, 0.1 nM, 5 μM, >10 μM and 15-70 nM respectively. This inhibition action has been used to stimulate the activity of glucose transport and has been observed to block insulin's stimulation of glucose transport by inhibiting IRS-1 phosphorylation. Okadaic Acid, Potassium Salt has been used as a response modifier in the study of large granular lymphocyte and T-cell biochemistry. In addition to inhibitive activities it is a tumor promoter and has been used to study nitric oxide metabolism, apoptosis, cell cycle and calcium signaling.
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed R38 - Irritating to skin
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Symbols:
T
Storage temperature :
-20°C
x
Alternative Distributors of [Okadaic Acid, Potassium Salt]
Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
Element: 
Chemical-Suppliers.eu