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1-oxazolo[4,5-b]pyridin-2-yl-9-octadecyn-1-one

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Formula: C24H34 N2 O2
CAS: 288862-89-5

Identification

Structural Formula
1-oxazolo[4,5-b]pyridin-2-yl-9-octadecyn-1-one
CAS:
288862-89-5
EINECS:
Molecular Formula:
C24H34 N2 O2
MDL:
SMILES:
CCCCCCCCC#CCCCCCCCC(=O)C1=NC2=C(O1)C=CC=N2
Synonym:
cay10401 ; 1-oxazolo[4,5-b]pyridin-2-yl-9-octadecyn-1-one ; 9-octadecyn-1-one,1-oxazolo[4,5-b]pyridin-2-yl- ; 1-oxazolo[4,5-b]pyridin-2-yl-octadeca-9-yn-1-one


Description

1-oxazolo[4,5-b]pyridin-2-yl-9-octadecyn-1-one is a selective, potent inhibitor of rat FAAH exhibiting a Ki value of 0.14 nM. Fatty acid amide hydrolase (FAAH) is the enzyme responsible for inactivation and hydrolysis of fatty acid amides including anandamide and oleamide. 1-oxazolo[4,5-b]pyridin-2-yl-9-octadecyn-1-one is approximately 580 fold more potent than oleyl trifluoromethyl ketone when assayed under the same conditions.


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Santa Cruz Biotechnology, Inc.
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Dayang Chem (Hangzhou) Co.,Ltd.
DC855634224
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Properties for 1-oxazolo[4,5-b]pyridin-2-yl-9-octadecyn-1-one

Molecular Weight:
382.53896 g·mol−1
Density:
1.03 g/mL (Predicted)
Melting point:
207.02° C (Predicted)
Boiling point:
508.28° C at 760 mmHg (Predicted)
Solubility:
Soluble in water (0.15 mg/ml at 25° C), ethanol (~20 mg/ml), DMSO (~20 mg/ml), DMF (~20 mg/ml), and 1:1 solution of DMSO:PBS (pH 7.2) (~0.15 mg/ml).
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Alternative Distributors of [1-oxazolo[4,5-b]pyridin-2-yl-9-octadecyn-1-one]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Mol File:
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MSDS:
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