Pamidronate disodium salt | CAS 57248-88-1

Element: pamidronate disodium salt

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Identification

Pamidronate disodium salt

CAS:

57248-88-1

EINECS:

260-647-1

Molecular Formula:

C₃H₉NNa₂O₇P₂.xH₂O

MDL:

MFCD11045314

SMILES:

C(CN)C(O)(P(=O)(O)[O-])P(=O)(O)[O-].[Na+].[Na+]

Synonym:

pamidronate disodium salt ; pamidronate (pamidronic acid) ; disodium pamidronate ; pamidronate disodium salt hydrate ; pamidronate disodium api ; pamidronate ; cgp 23339ae ; disodium pamidronate hydrate ; cgp23339a ; pamidronicdisodiumsalt

Description

Pamidronate disodium salt is a bisphosphonate compound, which inhibits farnesyl diphosphate synthase and bone resorption. Studies suggest that Pamidronate disodium salt stimulates polymorphonuclear leukocyte and platelet derived nitric oxide production. It is believed that this nitric oxide production can lead to a negative feedback mechanism, which could restrict the inflammatory process and reduce bone resorption. Furthermore, bisphosphonates induce endothelial cell death, cancer cell apoptosis, and nuclear factor-κB pathway activation, via the endothelial protein C receptor.

Suppliers

Hangzhou Lingrui Chemical Co., Ltd.

HLC262510500

Wanko Chemical Co., Ltd.

WC18005400

Leap Chem Co., Ltd

LC13504050

Santa Cruz Biotechnology, Inc.

272006

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CAS equal suppliers

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TCI Chemicals (India) Pvt. Ltd.

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sc-208147

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CM Fine Chemicals

CFC19727888

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Huateng Pharmaceutical Co.,Ltd

2061336

Pamidronate Disodium Pentahydrate

Santa Cruz Biotechnology, Inc.

sc-272006

Pamidronic acid, sodium salt hydrate

AK Scientific, Inc.

AS342010260

Phosphonic acid, (3-amino-1-hydroxypropylidene)bis-, disodium salt

Angene International Limited

AGN-PC-0SNA2A

Prices & Availability

Data is processed

Properties for Pamidronate disodium salt

Molecular Weight:

279.03 g·mol−1

Melting point:

300 °C

Solubility:

H₂O: 28 mg/mL

Safety & Transport Information

Risk Codes:

R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R22 - Harmful if swallowed
R37/38 - Irritating to respiratory system and skin
R41 - Risk of serious damage to eyes
R48 - Danger of serious damage to health by prolonged exposure

Safety Codes:

S22 - Do not breathe dust
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)

Hazard Classes:

irritant

Hazard Symbols:

Storage temperature :

2-8°C

Alternative Distributors of [Pamidronate disodium salt]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

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