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PGD2 (Prostaglandin D2)

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Formula: C20H32O5
CAS: 41598-07-6
search Element: prostaglandin pgd2

Identification

Structural Formula
PGD2 (Prostaglandin D2)
CAS:
41598-07-6
EINECS:
Molecular Formula:
C20H32O5
MDL:
MFCD00077857
SMILES:
CCCCC[C@@H](/C=C/[C@@H]1[C@H]([C@H](CC1=O)O)C/C=CCCCC(=O)O)O
Synonym:
prostaglandins d2 ; pgd2 (prostaglandin d2) ; pgds ; prostaglandind2synthetichygroscopic ; pgd2 ; 11-dehydroprostaglandinf2-alpha ; rp23-47p18.11-006, 21kda ; prostaglandin d2 cell culture tested ; prostaglandin d2 ; prostaglandin d2 synthase (brain)


Description

PGD2 (Prostaglandin D2) is a major cellular regulator synthesized from arachidonic acid via the catalytic activities of cyclooxygenases (COX) and PGD2 synthases (PGDS) in mast cells, macrophages and other cellular sources. PGD2 has been shown to bind DP and CRTH2 receptors, and reportedly inhibits platelet aggregation, proliferation of cells, and activation of neutrophils. This compound is also a potent vasodilator that also relaxes smooth muscle, but causes contraction of the bronchial airways. Furthermore, PGD2 is thought to be involved with sleep regulation it has been shown to lower the body temperature and induce normal sleep. PGD2 (Prostaglandin D2) is an activator of DP2 and DP.


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Santa Cruz Biotechnology, Inc.
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Properties for PGD2 (Prostaglandin D2)

Molecular Weight:
352.47 g·mol−1
Density:
1.15 g/cm3
Melting point:
58-60° C
Boiling point:
549.61° C at 760 mmHg
Solubility:
Soluble in ethanol (100 mg/ml), PBS (pH 7.2) (~5 mg/ml), acetone, ethyl acetate, DMF (~50 mg/ml), DMSO (~50 mg/ml), and methanol.
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Safety & Transport Information

Risk Codes:
R22 - Harmful if swallowed
R60 - May impair fertility
Safety Codes:
S22 - Do not breathe dust
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S53 - Avoid exposure - obtain special instructions before use
Hazard Symbols:
T
Hazard symbol T
Storage temperature :
-20°C
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Alternative Distributors of [PGD2 (Prostaglandin D2)]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Mol File:
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MSDS:
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