PGJ2 (Prostaglandin J2) is biosynthesized via nonenzymatic dehydration of PGD2, a process which is accelerated by the presence of albumin. PGJ2 has been show to inhibit platelet aggregation (IC50 ~ 5-10 nM), aortic smooth muscle cell proliferation, and phosphoinositide turnover. Has also been shown to exhibit potent anti-neoplastic and antiviral activity. Much of the activity associated with PGJ2 has been attributed to downstream metabolites such as 15-Deoxy-δ12,14-Prostaglandin J2. PGJ2 (Prostaglandin J2) is an inhibitor of PPARα and PPARγ .
Soluble in ethanol (100 mg/ml), DMSO (100 mg/ml), and acetone.
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Safety & Transport Information
Risk Codes:
R11 - Highly flammable R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed R36 - Irritating to eyes R36/37/38 - Irritating to eyes, respiratory system and skin R66 - Repeated exposure may cause skin dryness or cracking R67 - Vapours may cause drowsiness and dizziness
Safety Codes:
S16 - Keep away from sources of ignition - No smoking S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice S29 - Do not empty into drains S33 - Take precautionary measures against static discharges S36 - Wear suitable protective clothing
Hazard Symbols:
Xn, Xi, F
Storage temperature :
-20°C
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Alternative Distributors of [PGJ2 (Prostaglandin J2)]
Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
Element: 
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