17-Phenyl-trinor-prostaglandin E2 | CAS 38315-43-4

Element: prostaglandin phenyl trinor

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Identification

17-Phenyl-trinor-prostaglandin E2

CAS:

38315-43-4

EINECS:

Molecular Formula:

C₂₃H₃₀O₅

MDL:

SMILES:

C1C(C(C(C1=O)CC=CCCCC(=O)O)C=CC(CCC2=CC=CC=C2)O)O

Synonym:

17-phenyl-trinor-prostaglandin e2 98% ; 17-phenyl-18,19,20-trinor-pge2 ; cl 116147 ; 9-oxo-11alpha-15s-dihydroxy-17-phenyl-18,19,20-trinor-prosta-5z,13e-dien-1-oic acid ; 17-phenyl-omega-trinor-pge2 ; 17-phenyl trinor prostaglandin e2 99+% ; 17-phenyl trinor prostaglandin e2 ; 17-phenyl-18,19,20-trinorprostaglandin e2 ; 17-phenyltrinorprostaglandinee2

Description

17-Phenyl-trinor-prostaglandin E₂ is a synthetic analog of prostaglandin E₂ (PGE₂), that was found to be a selective EP₁ and EP₃ receptor agonist, unlike PGE₂ which antagonizes a variety of EP receptors. 17-Phenyl-trinor-prostaglandin E₂ has been shown to cause contraction of the guinea pig ileum at a concentration of 11 μM, and is slightly less potent than PGE₂ in stimulating gerbil colon and rat uterus. 17-Phenyl-trinor-prostaglandin E₂ has an ED₅₀ value of 350 μg/kg, and is 4.4 times more potent than PGE₂ as an antifertility agent in hamsters.