Pioglitazone | CAS 111025-46-8 | Chemical-Suppliers

Element: pioglitazone

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C-S » Chemicals » pioglitazone-PX69799

Identification

Pioglitazone

CAS:

111025-46-8

EINECS:

Molecular Formula:

C₁₉H₂₀N₂O₃S

MDL:

MFCD00865504

SMILES:

CCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3

Synonym:

5-[4-[2-(5-ethyl-2-pyridinyl)ethoxy]benzyl]thiazolidine-2,4-dione ; pioglitazone free base ; pioglitazone ; 2,4-thiazolidinedione,5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]- ; pinepollen ; 5-(4-[2-(5-ethyl-pyridin-2-yl)-ethoxy]-benzyl)-thiazolidine-2,4-dione ; 5-[4-[2-(5-ethyl-2-pyridyl)ethoxy]benzyl]thiazolidine-2,4-dione ; pioglitazone (actos) ; pioglitazone and its intermeidates ; 5-[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl-2,4-thiazolidinedione

Description

Pioglitazone, a thaizolidinedione derivative, has been shown to be a high affinity ligand for the peroxisome proliferator-activated receptor (PPAR), specifically PPARγ1 and PPARα activator. Binding assays have indicated that this activation is due to direct binding of pioglitazone to each subtype. It has been noted that this agent promotes adipocyte differentiation of mesenchymal and preadipocyte stem cell lines In vitro. Additionally, pioglitazone is an inhibitor of NF κB.

Suppliers

H&Z Industry Co.,Ltd

HIC240960

Xiamen Equation Chemical Co.,Ltd

XECC3841920

CSNpharm, Inc.

CSN10029

Finetech Industry Limited

FIL3001200

Carbone Scientific Co., Ltd.

CS3361008

Hefei Hirisun Pharmatech Co., Ltd

HR013676

AK Scientific, Inc.

AS228684

Xingrui Industry Co., Limited

XIL3481392

BOC Sciences

BS144432

Leap Chem Co., Ltd

LC216648

Santa Cruz Biotechnology, Inc.

202289

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CAS equal suppliers

Pioglitazone-d4

Santa Cruz Biotechnology, Inc.

sc-219625

Pioglitazone - Labeled d4

Santa Cruz Biotechnology, Inc.

sc-355945

5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione

BLD Pharmatech Ltd

BP1053031590

Prices & Availability

Data is processed

Properties for Pioglitazone

Molecular Weight:

356.44 g·mol−1

Density:

1.26 g/cm³ (Predicted)

Melting point:

183-184 C

Boiling point:

575.45° C at 760 mmHg (Predicted)

Solubility:

Soluble in water (<1 mg/ml at 25° C), DMSO (15 mg/ml at 25° C), DMF (2.5 mg/ml), ethanol (<1 mg/ml at 25° C), and 1:1 solution of DMSO:PBS (pH 7.2) (~ 0.1 mg/ml).

Safety & Transport Information

Risk Codes:

R11 - Highly flammable
R34 - Causes burns

Safety Codes:

S16 - Keep away from sources of ignition - No smoking
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)

Hazard Symbols:

F, C

Alternative Distributors of [Pioglitazone]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified