Pitavastatin Calcium | CAS 147526-32-7

Element: pitavastatin calcium

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C-S » Chemicals » pitavastatin-calcium-PX71304

Identification

Pitavastatin Calcium

CAS:

147526-32-7

EINECS:

Molecular Formula:

(C₂₅H₂₃FNO₄)₂Ca

MDL:

MFCD01937979

SMILES:

O[C@H](/C=C/c1c(nc2ccccc2c1c1ccc(F)cc1)C1CC1)C[C@@H](O)CC(=O)O[Ca]OC(=O)C[C@H](O)C[C@H](O)/C=C/c1c(nc2ccccc2c1c1ccc(F)cc1)C1CC1

Synonym:

nk104(acid) ; nk-104 calcium ; nk104 ; itavastatin calcium ; d01862 ; pitavasttin calcium ; itavastatin ca ; pitavastatin calcium ; pitavastatin calcuim ; pitavastatinhemicalcium

Description

Pitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR (HMG-CoA reductase) results in a reduction in LDL cholesterol synthesis. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting Nox (NADPH oxidase). In addition, pitavastatin reduces the expression of eNOS mRNA while increasing the NO dependent response stimulated by acetylcholine and the calcium ionophore, A23187. Furthermore, pitavastatin inhibits the up-regulation of conductance calcium-activated potassium channels by lowering cholesterol levels in cells.

Suppliers

Shandong SanYoung Industry Co., Ltd

SSI14005600

Ambeed, Inc.

A135712

Aozeal Certified Standards (AOCS), Inc.

P0071.00

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI276011040

Shandong Minglang Chemical Co., Ltd

SMC14005600

H&Z Industry Co.,Ltd

HIC8003200

JieJie Group Co., Ltd.

JG8802640

Arcadia Biotechnology

AB8402520

Xiamen Equation Chemical Co.,Ltd

XECC12806400

Aecochem Corp.

AC5601680

CSNpharm, Inc.

CSN11738

Finetech Industry Limited

FIL10004000

Pharmacore Co., Limited

PL9202760

Hefei Hirisun Pharmatech Co., Ltd

HR013239

AK Scientific, Inc.

AS7602280

Simagchem Corporation

SC8402520

Xingrui Industry Co., Limited

XIL11604640

BOC Sciences

BS4801440

Leap Chem Co., Ltd

LC7202160

Santa Cruz Biotechnology, Inc.

208176

Dayang Chem (Hangzhou) Co.,Ltd.

DC12404960

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CAS equal suppliers

Pevastatin calcium

Jiwan Pharmaceutical Technology Co., Ltd.

JPT14765904

Pitavastatin calcium salt

Molekula

58656411

Calcium; 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoate

Salsbury Chemicals, Inc.

SC2040061200

Calcium bis{(3R,5S,6E)-7-[2-cyclopyl-4-(4-fluorophenyl)-3-quinolyl]-3,5-dihydroxy-6-heptenoate}

BLD Pharmatech Ltd

BP2565076950

(+)-Monocalcium-bis{(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3,5-dihydroxy-6-heptenoate}

Haihang Industry Co., Ltd.

HI38584115752

Prices & Availability

Data is processed

Properties for Pitavastatin Calcium

Molecular Weight:

880.98 g·mol−1

Boiling point:

692° C at 760 mmHg

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Alternative Distributors of [Pitavastatin Calcium]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified