PKI (6-22) amide | CAS 121932-06-7

Element: amide

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C-S » Chemicals » pki-amide-PX69253

Identification

PKI (6-22) amide

CAS:

121932-06-7

EINECS:

Molecular Formula:

C₈₀H₁₃₀ N₂₈ O₂₄

MDL:

MFCD00133792

SMILES:

[H]/N=C(N)/NCCC[C@@H](C(=O)N[C@@H](CCCN/C(=N/[H])/N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N)NC(=O)CNC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCN/C(=N/[H])/N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](Cc2ccc(cc2)O)NC(=O)[C@H]([C@@H](C)O)N

Synonym:

pka inhibitor 6-22-amide ; protein kinase a inhibitor fragment 6-22 amide ; pki 6-22 amide, pka inhibitor ; tyadfiasgrtgrrnai-nh2 ; protein kinase inhibitor (6-22) amide ; 4:pn: us20090092566 seqid: 4 claimed protein ; pka inhibitor peptide ; pka inhibitor fragment (6-22) amide ; proteinkinase a inhibitor 6-22-amide ; pki inhibitor (6-22), amide ; pki (6-22) amide ; l-isoleucinamide,l-threonyl-l-tyrosyl-l-alanyl-l-a-aspartyl-l-phenylalanyl-l-isoleucyl-l-alanyl-l-serylglycyl-l-arginyl-l-threonylglycyl-l-arginyl-l-arginyl-l-asparaginyl-l-alanyl- ; protein kinase a inhibitor 6-22 amide ; tyadfiasgrtgrrnai

Description

PKI (6-22) amide is a synthetic peptide that acts as a protein kinase inhibitor. The compound has been shown to inhibit PKA by binding to the substrate site of PKA (IC₅₀ < 2 nM). MDA-MB231 breast cancer cell research indicates that the antiproliferative effects of PKI (6-22) amide are associated to the cAMP-PKA pathway, due to its ability to revert the effects of oxytocin.

Suppliers

Santa Cruz Biotechnology, Inc.

201160

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Santa Cruz Biotechnology, Inc.

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Dayang Chem (Hangzhou) Co.,Ltd.

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Leap Chem Co., Ltd

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Prices & Availability

Data is processed

Properties for PKI (6-22) amide

Molecular Weight:

1868.06 g·mol−1

Density:

~1.5 g/cm³ (Predicted)

Safety & Transport Information

Storage temperature :

-20°C

Alternative Distributors of [PKI (6-22) amide]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Salsbury Chemicals, Inc.,