PKSI-527 | CAS 128837-71-8 | Chemical-Suppliers

Element: pksi

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C-S » Chemicals » pksi-PX76826

Identification

PKSI-527

CAS:

128837-71-8

EINECS:

Molecular Formula:

C₂₅H₃₁ N₃ O₄ . Cl H

MDL:

SMILES:

C1CC(CCC1CN)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)NC3=CC=C(C=C3)CC(=O)O.Cl

Synonym:

Benzeneaceticacid,4-[[2-[[[4-(aminomethyl)cyclohexyl]carbonyl]amino]-1-oxo-3-phenylpropyl]amino]-,monohydrochloride, [1(S)-trans]- ; PKSI 527 ; Benzeneacetic acid,4-[[(2S)-2-[[[trans-4-(aminomethyl)cyclohexyl]carbonyl]amino]-1-oxo-3-phenylpropyl]amino]-,monohydrochloride (9CI)

Description

PKSI-527 is a highly selective plasma kallikrein inhibitor (K_i = 0.81 μM) which can be used for affinity purification of kalikrein. It suppresses collagen-induced arthritis in a mouse model. Additionally, PKSI-527 has been shown to synergize with NO donors producing antithrombotic effects.

Suppliers

Santa Cruz Biotechnology, Inc.

222181

Dayang Chem (Hangzhou) Co.,Ltd.

DC248992

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Prices & Availability

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Properties for PKSI-527

Molecular Weight:

473.9923 g·mol−1

Boiling point:

763.1°C at 760 mmHg

Flash point:

415.3°C

Solubility:

Soluble in water (5 mg/ml).

Safety & Transport Information

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Alternative Distributors of [PKSI-527]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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MSDS:

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