L-Proline 7-amido-4-methylcoumarin hydrobromide

Fluorogenic substrate for detection of L-proline aminopeptidase. Yields a blue fluorescent solution upon cleavage. e.g. for differentiation within Candida species, Enterobacteriaceae and pathogenic Neisseriaceae species. 1. D'Amato R.F., Eriquez L.A., Tomfohrde K.M., Singerman E., Rapid identification of Neisseria gonorrhoeae and Neisseria meningitidis by using enzymatic profiles. J. Clin. Microbiol. 1978, 7, 77-81. 2. Fanhänel S., Reisbrodt R., Giesecke H., L-prolineaminopeptidase activity as a tool for identification and differentiation of Serratia marcescens, Serratia liquefaciens and Hafnia alvei strains. Zbl. Bakt. 1991, 275, 11-5. 3. Godsey J.H., Matteo M.R., Shen D., Tolman G., Gohlke J.R., Rapid identification of Enterobacteriaceae with microbial enzyme activity profiles. J. Clin. Microbiol. 1981, 13, 483-90.