15(R)-Prostaglandin E2 | CAS 38873-82-4

Element: prostaglandin

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C-S » Chemicals » prostaglandin-PX80008

Identification

15(R)-Prostaglandin E2

CAS:

38873-82-4

EINECS:

Molecular Formula:

C₂₀H₃₂O₅

MDL:

SMILES:

O=C1[C@H](C/C=CCCCC(O)=O)[C@@H](/C=C/[C@H](O)CCCCC)[C@H](O)C1

Synonym:

9-oxo-11alpha,15r-dihydroxy-prosta-5z,13e-dien-1-oic acid ; 15(r)-prostaglandin e2 ; 15-epi pge2

Description

15(R)-Prostaglandin E2 is the C-15 epimer of the naturally occurring 15(S)-PGE2 isomer; the most physiologically abundant eicosanoid, which is produced predominantly from arachidonic acid by COX and PGES, and exists at some level in nearly all cell types. PGE2 acts on four different receptors termed EP1 through EP4 yielding an astounding array of biological effects, but this compound shows much lower potency in most biological assays; however acid catalyzed epimerization can convert this compound to the active form - 15(S)-Prostaglandin E2.