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Pyrazolylpyrrole ERK Inhibitor

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Formula: C22H17Cl2FN4O2
CAS: 933786-58-4
search Element: pyrazolylpyrrole inhibitor
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Identification

Structural Formula
Pyrazolylpyrrole ERK Inhibitor
CAS:
933786-58-4
EINECS:
Molecular Formula:
C22H17Cl2FN4O2
MDL:
SMILES:
C1=CC(=CC(=C1)Cl)C2=CNNC2=C3C=C(N=C3)C(=O)NC(CO)C4=CC(=C(C=C4)F)Cl
Synonym:
cay10561 exclusive ; pyrazolylpyrrole erk inhibitor ; cay10561


Description

Pyrazolylpyrrole ERK Inhibitor is a potent, ATP-competitive inhibitor of ERK2 (Ki = 2 nM). This compound is highly selective for ERK2 compared to other kinases such as PKA (Ki = 0.39 µM) and JNK3 (Ki = 4 µM). Inhibits proliferation of Colo205 cells with an IC50 value of 0.54 µM.


Suppliers

Santa Cruz Biotechnology, Inc.
222229
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Prices & Availability




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Properties for Pyrazolylpyrrole ERK Inhibitor

Molecular Weight:
459.30 g·mol−1
Solubility:
Soluble in 1:1 ethanol:PBS (pH 7.2) (~0.5 mg/ml), ethanol (~ 5 mg/ml), DMSO (~ 1.5 mg/ml), and DMF (~ 2.5 mg/ml).
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Alternative Distributors of [Pyrazolylpyrrole ERK Inhibitor]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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